Clearance by the rat of inhaled fly ash from fluidized-bed coal combustion
Fly ash from a fluidized-bed coal combustor was neutron-activated and administered to male Fischer 344 rats by a single nose-only inhalation exposure. The activated fly ash contained /sup 46/Sc and smaller amounts of other gamma-emitting radionuclides. Whole-body clearance of radioactivity of 127 d was described by an exponential equation, with the long-term component having a biological half-life of 78 d. High-resolution gamma spectra of the lungs was obtained with a Ge(Li) detector and the relative activities of several fly ash constituents were compared. The activities of /sup 152/Eu, /sup 134/Cs, /sup 54/Mn, and /sup 60/Co significantly decreased with time relative to those of /sup 46/Sc and /sup 59/Fe. These results indicate that the clearance of fly ash is similar to that of other relatively insoluble particles and that some elements may have been preferentially dissolved from the fly ash particles in vivo.
- Research Organization:
- Lovelace Inhalation Toxicology Research Institute, Albuquerque, NM
- DOE Contract Number:
- AC04-76EV01013
- OSTI ID:
- 6459588
- Journal Information:
- J. Toxicol. Environ. Health; (United States), Vol. 7:1
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
59 BASIC BIOLOGICAL SCIENCES
02 PETROLEUM
FLUIDIZED-BED COMBUSTION
ENVIRONMENTAL EFFECTS
FLY ASH
LUNG CLEARANCE
ACTIVATION ANALYSIS
BIOLOGICAL HALF-LIFE
BIOLOGICAL MODELS
CESIUM 134
COAL
COBALT 60
EUROPIUM 152
IN VIVO
INHALATION
IRON 59
LUNGS
MANGANESE 54
NEUTRONS
PARTICLES
RADIONUCLIDE KINETICS
RATS
SCANDIUM 46
TRACER TECHNIQUES
AEROSOL WASTES
ALKALI METAL ISOTOPES
ANIMALS
ASHES
BARYONS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BODY
CARBONACEOUS MATERIALS
CESIUM ISOTOPES
CHEMICAL ANALYSIS
CHEMICAL REACTIONS
CLEARANCE
COBALT ISOTOPES
COMBUSTION
DAYS LIVING RADIOISOTOPES
ELECTRON CAPTURE RADIOISOTOPES
ELEMENTARY PARTICLES
ENERGY SOURCES
EUROPIUM ISOTOPES
EVEN-ODD NUCLEI
EXCRETION
FERMIONS
FOSSIL FUELS
FUELS
HADRONS
HOURS LIVING RADIOISOTOPES
INTAKE
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IRON ISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
MAMMALS
MANGANESE ISOTOPES
MATERIALS
MINUTES LIVING RADIOISOTOPES
NUCLEI
NUCLEONS
ODD-ODD NUCLEI
ORGANS
OXIDATION
RADIOISOTOPES
RARE EARTH ISOTOPES
RARE EARTH NUCLEI
RESIDUES
RESPIRATORY SYSTEM
RODENTS
SCANDIUM ISOTOPES
SECONDS LIVING RADIOISOTOPES
THERMOCHEMICAL PROCESSES
VERTEBRATES
WASTES
YEARS LIVING RADIOISOTOPES
560305* - Chemicals Metabolism & Toxicology- Vertebrates- (-1987)
551001 - Physiological Systems- Tracer Techniques
560172 - Radiation Effects- Nuclide Kinetics & Toxicology- Animals- (-1987)
020900 - Petroleum- Environmental Aspects