Evaluation of acute radiation optic neuropathy by B-scan ultrasonography

Journal Article · Sat Sep 15 00:00:00 EDT 1990 · American Journal of Ophthalmology; (USA)

DOI:https://doi.org/10.1016/S0002-9394(14)76336-6· OSTI ID:6419801

Lovato, A A; Char, D H; Quivey, J M; Castro, J R ^[1]

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1. Univ. of California, San Francisco (USA)

We studied the accuracy of B-scan ultrasonography to diagnose radiation-induced optic neuropathy in 15 patients with uveal melanoma. Optic neuropathy was diagnosed by an observer masked as to clinical and photographic data. We analyzed planimetry area measurements of the retrobulbar nerve before and after irradiation. The retrobulbar area of the optic nerve shadow on B-scan was quantitated with a sonic digitizer. Increased optic nerve shadow area was confirmed in 13 of 15 patients who had radiation optic neuropathy (P less than .004). The correct diagnosis was confirmed when the results of ultrasound were compared to fundus photography and fluorescein angiography. In 13 patients there was acute radiation optic neuropathy. Two patients did not show an enlarged retrobulbar optic nerve, and the clinical appearance suggested early progression to optic atrophy. Ultrasonography documents the enlargement of the optic nerve caused by acute radiation changes.

• OSTI ID: 6419801
• Journal Information: American Journal of Ophthalmology; (USA), Vol. 110:3; ISSN 0002-9394
• Country of Publication: United States
• Language: English

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