Sham versus transurethral microwave thermotherapy in patients with symptoms of benign prostatic bladder outflow obstruction

Journal Article · Sat Jan 02 00:00:00 EST 1993 · Lancet; (United States)

DOI:https://doi.org/10.1016/0140-6736(93)92482-9· OSTI ID:6395809

Ogden, C W; Reddy, P; Johnson, H; Ramsay, J W; Carter, S C ^[1]

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1. Charing Cross Hospital, London (United Kingdom). Dept. of Urology

Transurethral microwave thermotherapy (TUMT) is a single-session, minimally invasive outpatient treatment for patients with symptoms of benign prostatic bladder outflow obstruction. The authors designed a prospective randomized trial to identify any placebo response. Patients with a Madsen symptom score over 8 for at least 6 months were eligible for study. Patients with renal dysfunction, upper urinary tract disease, co-existing bladder disease and malignant prostatic change were excluded. 43 patients were studied: 21 were randomized to receive a sham treatment and 22 to thermotherapy. The thermotherapy group showed a 70% decrease in the mean Madsen score, a 53% increase in flow-rate, and 92% decrease in residual urine volume. No Significant change was seen in these mean indices in the sham group. There was no difference in the main complication of transient hematuria between the two groups. However, there was a 22% frequency of acute retention in the TUMT group. The results show a little significant placebo component to the subjective and objective improvement that occurs in patients who have received TUMT.

• OSTI ID: 6395809
• Journal Information: Lancet; (United States), Vol. 341:8836; ISSN 0099-5355
• Country of Publication: United States
• Language: English

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