skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Development of a validation test for self-reported abstinence from smokeless tobacco products: preliminary results

Abstract

Using X-ray fluorescence spectrometry, 11 heavy elements at concentrations that are easily detectable have been identified in smokeless tobacco products. These concentrations were found to increase in cheek epithelium samples of the user after exposure to smokeless tobacco. This feasibility study suggests that the level of strontium in the cheek epithelium could be a valid measure of recent smokeless tobacco use. It also demonstrates that strontium levels become undetectable within several days of smokeless tobacco cessation. This absence of strontium could validate a self-report of abstinence from smokeless tobacco. Finally, the X-ray spectrum of heavy metal content of cheek epithelium from smokeless tobacco users could itself provide a visual stimulus to further motivate the user to terminate the use of smokeless tobacco products.

Authors:
;
Publication Date:
Research Org.:
East Carolina Univ., Greenville, NC (USA)
OSTI Identifier:
6321692
Resource Type:
Journal Article
Resource Relation:
Journal Name: Prev. Med.; (United States); Journal Volume: 17:4
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 59 BASIC BIOLOGICAL SCIENCES; STRONTIUM; SKIN ABSORPTION; TOBACCO PRODUCTS; HEALTH HAZARDS; EPITHELIUM; FEASIBILITY STUDIES; METABOLISM; MUCOUS MEMBRANES; ORAL CAVITY; VALIDATION; X-RAY SPECTRA; ABSORPTION; ALKALINE EARTH METALS; ANIMAL TISSUES; BODY; DIGESTIVE SYSTEM; ELEMENTS; HAZARDS; MEMBRANES; METALS; SPECTRA; TESTING; TISSUES; UPTAKE; 560300* - Chemicals Metabolism & Toxicology; 550501 - Metabolism- Tracer Techniques

Citation Formats

Robertson, J.B., and Bray, J.T. Development of a validation test for self-reported abstinence from smokeless tobacco products: preliminary results. United States: N. p., 1988. Web. doi:10.1016/0091-7435(88)90048-5.
Robertson, J.B., & Bray, J.T. Development of a validation test for self-reported abstinence from smokeless tobacco products: preliminary results. United States. doi:10.1016/0091-7435(88)90048-5.
Robertson, J.B., and Bray, J.T. Fri . "Development of a validation test for self-reported abstinence from smokeless tobacco products: preliminary results". United States. doi:10.1016/0091-7435(88)90048-5.
@article{osti_6321692,
title = {Development of a validation test for self-reported abstinence from smokeless tobacco products: preliminary results},
author = {Robertson, J.B. and Bray, J.T.},
abstractNote = {Using X-ray fluorescence spectrometry, 11 heavy elements at concentrations that are easily detectable have been identified in smokeless tobacco products. These concentrations were found to increase in cheek epithelium samples of the user after exposure to smokeless tobacco. This feasibility study suggests that the level of strontium in the cheek epithelium could be a valid measure of recent smokeless tobacco use. It also demonstrates that strontium levels become undetectable within several days of smokeless tobacco cessation. This absence of strontium could validate a self-report of abstinence from smokeless tobacco. Finally, the X-ray spectrum of heavy metal content of cheek epithelium from smokeless tobacco users could itself provide a visual stimulus to further motivate the user to terminate the use of smokeless tobacco products.},
doi = {10.1016/0091-7435(88)90048-5},
journal = {Prev. Med.; (United States)},
number = ,
volume = 17:4,
place = {United States},
year = {Fri Jul 01 00:00:00 EDT 1988},
month = {Fri Jul 01 00:00:00 EDT 1988}
}