skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Radionuclide computed tomography of the body using routine radiopharmaceuticals. II. Clinical applications

Abstract

A whole-body computed tomography system for single-photon emitters was used to investigate the clinical utility of this imaging modality. We have explored its application in brain, lung, liver, kidney, cardiac, bone, and gallium imaging in over 200 patients. Brain images demonstrated better lesion contrast than that in standard scintiphotos. Images of the lung and liver showed radionuclide distribution that was not readily apparent in standard scintiphotos. Moderate or strongly positive pyrophosphate myocardial images demonstrate the potential for infarct quantitation. ECG-gated cardiac blood-pool images in cross section, displayed in cine formate, permit evaluation of segmental motion of the free and septal walls of both ventricles. These results suggest significant clinical potential for this imaging modality using standard radiopharmaceuticals, but some increase in system sensitivity will likely be necessary to realize the full benefit of the technique.

Authors:
; ;
Publication Date:
Research Org.:
Baylor Coll., Houston, TX
OSTI Identifier:
6295451
Resource Type:
Journal Article
Journal Name:
J. Nucl. Med.; (United States)
Additional Journal Information:
Journal Volume: 20:2
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ECAT SCANNING; RESOLUTION; SENSITIVITY; BLADDER; BRAIN; KIDNEYS; LIVER; LUNGS; MYOCARDIUM; SKELETON; TECHNETIUM 99; ABDOMEN; CHEST; GALLIUM 67; THALLIUM 201; PATIENTS; ISOMERIC NUCLEI; RADIOPHARMACEUTICALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; BODY AREAS; CARDIOVASCULAR SYSTEM; CAT SCANNING; CENTRAL NERVOUS SYSTEM; DAYS LIVING RADIOISOTOPES; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; GALLIUM ISOTOPES; GLANDS; HEART; HEAVY NUCLEI; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; MUSCLES; NERVOUS SYSTEM; NUCLEI; ODD-EVEN NUCLEI; ORGANS; PHOTON EMISSION SCANNING; PHOTON TRANSMISSION SCANNING; RADIOACTIVE MATERIALS; RADIOISOTOPES; RESPIRATORY SYSTEM; SECONDS LIVING RADIOISOTOPES; TECHNETIUM ISOTOPES; THALLIUM ISOTOPES; TOMOGRAPHY; URINARY TRACT; YEARS LIVING RADIOISOTOPES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics

Citation Formats

Burdine, J.A., Murphy, P.H., and DePuey, E.G. Radionuclide computed tomography of the body using routine radiopharmaceuticals. II. Clinical applications. United States: N. p., 1979. Web.
Burdine, J.A., Murphy, P.H., & DePuey, E.G. Radionuclide computed tomography of the body using routine radiopharmaceuticals. II. Clinical applications. United States.
Burdine, J.A., Murphy, P.H., and DePuey, E.G. Thu . "Radionuclide computed tomography of the body using routine radiopharmaceuticals. II. Clinical applications". United States.
@article{osti_6295451,
title = {Radionuclide computed tomography of the body using routine radiopharmaceuticals. II. Clinical applications},
author = {Burdine, J.A. and Murphy, P.H. and DePuey, E.G.},
abstractNote = {A whole-body computed tomography system for single-photon emitters was used to investigate the clinical utility of this imaging modality. We have explored its application in brain, lung, liver, kidney, cardiac, bone, and gallium imaging in over 200 patients. Brain images demonstrated better lesion contrast than that in standard scintiphotos. Images of the lung and liver showed radionuclide distribution that was not readily apparent in standard scintiphotos. Moderate or strongly positive pyrophosphate myocardial images demonstrate the potential for infarct quantitation. ECG-gated cardiac blood-pool images in cross section, displayed in cine formate, permit evaluation of segmental motion of the free and septal walls of both ventricles. These results suggest significant clinical potential for this imaging modality using standard radiopharmaceuticals, but some increase in system sensitivity will likely be necessary to realize the full benefit of the technique.},
doi = {},
journal = {J. Nucl. Med.; (United States)},
number = ,
volume = 20:2,
place = {United States},
year = {1979},
month = {2}
}