Prospects for antibody-targeted radiotherapy of cancer

Journal Article · Sat Sep 06 00:00:00 EDT 1986 · Lancet; (United States)

DOI:https://doi.org/10.1016/S0140-6736(86)90150-9· OSTI ID:6281469

Wheldon, T E; O'Donoghue, J A; Epenetos, A A

In this series of letters, the prospects for antibody-targeted radiotherapy of cancer are reviewed. Issues discussed include modelling, especially in connection with purging tumour cells from bone marrow as part of leukemia treatment, and the application of models to regional intracavity instillation (e.g. ovarian cancer), the distribution of radioactivity throughout the tumour mass and the tumour volume doubling time. (U.K.).

• Research Organization: Belvidere Hospital, Glasgow, UK. Inst. of Radiotherapeutics; Western Regional Hospital Board, Glasgow, UK. Dept. of Clinical Physics and Bio-Engineering; Royal Postgraduate Medical School, London, UK
• OSTI ID: 6281469
• Journal Information: Lancet; (United States), Vol. 2:8506; Other Information: Letters to the editor
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
RADIOIMMUNOTHERAPY
EVALUATION
INTERNAL IRRADIATION
IODINE 131
LEUKEMIA
MATHEMATICAL MODELS
MONOCLONAL ANTIBODIES
OVARIES
RADIATION DOSES
ANTIBODIES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
DAYS LIVING RADIOISOTOPES
DISEASES
DOSES
FEMALE GENITALS
GONADS
HEMIC DISEASES
IMMUNOLOGY
INTERMEDIATE MASS NUCLEI
IODINE ISOTOPES
IRRADIATION
ISOTOPES
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOIMMUNOLOGY
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
THERAPY
550604* - Medicine- Unsealed Radionuclides in Therapy- (1980-)