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Title: Quantitative analysis of low molecular weight carboxylic acids by capillary zone electrophoresis/conductivity detection

Abstract

Low molecular weight carboxylic acids are separated and quantitated by capillary zone electrophoresis (CZE) with an on-column conductivity detector. The addition of 0.2-0.5 mM TTAB (tetradecyltrimethylammonium bromide) controls the electroosmotic flow so that all carboxylate anions pass through the detector. Unlike other CZE detection methods, conductivity detection shows a direct relationship between retention time and peak area. This confers on conductivity detection, in CZE, the unique advantage that use of an internal standard allows accurate determination of absolute concentrations in a mixture without separate calibration of response for each component.

Authors:
; ; ;
Publication Date:
Research Org.:
Stanford Univ., CA (USA)
OSTI Identifier:
6224122
Resource Type:
Journal Article
Journal Name:
Anal. Chem.; (United States)
Additional Journal Information:
Journal Volume: 61:7
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; 54 ENVIRONMENTAL SCIENCES; CARBOXYLIC ACIDS; ELECTROPHORESIS; VOLTAMETRY; LACTATES; MILK PRODUCTS; QUANTITATIVE CHEMICAL ANALYSIS; WATER; CALIBRATION STANDARDS; CAPILLARIES; EXPERIMENTAL DATA; MOLECULAR WEIGHT; TIME DEPENDENCE; BLOOD VESSELS; BODY; CARBOXYLIC ACID SALTS; CARDIOVASCULAR SYSTEM; CHEMICAL ANALYSIS; DATA; FOOD; HYDROGEN COMPOUNDS; INFORMATION; NUMERICAL DATA; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANS; OXYGEN COMPOUNDS; STANDARDS; 400102* - Chemical & Spectral Procedures; 400105 - Separation Procedures; 520200 - Environment, Aquatic- Chemicals Monitoring & Transport- (-1989)

Citation Formats

Huang, X, Luckey, J A, Gordon, M J, and Zare, R N. Quantitative analysis of low molecular weight carboxylic acids by capillary zone electrophoresis/conductivity detection. United States: N. p., 1989. Web. doi:10.1021/ac00182a025.
Huang, X, Luckey, J A, Gordon, M J, & Zare, R N. Quantitative analysis of low molecular weight carboxylic acids by capillary zone electrophoresis/conductivity detection. United States. doi:10.1021/ac00182a025.
Huang, X, Luckey, J A, Gordon, M J, and Zare, R N. Sat . "Quantitative analysis of low molecular weight carboxylic acids by capillary zone electrophoresis/conductivity detection". United States. doi:10.1021/ac00182a025.
@article{osti_6224122,
title = {Quantitative analysis of low molecular weight carboxylic acids by capillary zone electrophoresis/conductivity detection},
author = {Huang, X and Luckey, J A and Gordon, M J and Zare, R N},
abstractNote = {Low molecular weight carboxylic acids are separated and quantitated by capillary zone electrophoresis (CZE) with an on-column conductivity detector. The addition of 0.2-0.5 mM TTAB (tetradecyltrimethylammonium bromide) controls the electroosmotic flow so that all carboxylate anions pass through the detector. Unlike other CZE detection methods, conductivity detection shows a direct relationship between retention time and peak area. This confers on conductivity detection, in CZE, the unique advantage that use of an internal standard allows accurate determination of absolute concentrations in a mixture without separate calibration of response for each component.},
doi = {10.1021/ac00182a025},
journal = {Anal. Chem.; (United States)},
number = ,
volume = 61:7,
place = {United States},
year = {1989},
month = {4}
}