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Title: Computer-assisted liver-mass estimation from gamma-camera images. [/sup 99m/Tc-sulfur colloid imaging]

Abstract

We have devised a computer-assisted method for objective estimation of liver mass from the right lateral projection of radiocolloid images of the liver. Gamma-camera images were digitized, preprocessed, and stored in computer memory. The definition of liver for area measurement was adaptively determined by means of a Laplacian operator that measures change in radioactivity slope associated with the liver margin. Individual thresholds were calculated for each of 16 subregions. A liver-mass index was derived from a linear regression model correlating the area of the right lateral projection with liver weight at autopsy in 50 patients whose livers weighed between 0.8 to 3.0 Kg. The correlation coefficient found for this method was 0.83 using the equation: Liver Mass (kg) = Area (cm/sup 2/)/275 (kg/cm/sup 2/) - 0.215 (kg). Liver-mass estimates using an alternative computer-assisted method or representative manual methods adapted for gamma-camera images showed lower correlation with liver weight at autopsy.

Authors:
; ; ;
Publication Date:
Research Org.:
Univ. of South Florida, Tampa
OSTI Identifier:
6165496
Resource Type:
Journal Article
Journal Name:
J. Nucl. Med.; (United States)
Additional Journal Information:
Journal Volume: 20:2
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; GAMMA CAMERAS; IMAGE PROCESSING; LIVER; SCINTISCANNING; TECHNETIUM 99; COMPUTERS; ISOMERIC NUCLEI; LAPLACIAN; PATIENTS; RADIOCOLLOIDS; SULFUR COMPLEXES; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CAMERAS; COLLOIDS; COMPLEXES; COUNTING TECHNIQUES; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM; DISPERSIONS; GLANDS; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MATHEMATICAL OPERATORS; NUCLEI; ODD-EVEN NUCLEI; ORGANS; RADIOISOTOPE SCANNING; RADIOISOTOPES; TECHNETIUM ISOTOPES; YEARS LIVING RADIOISOTOPES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics

Citation Formats

Eikman, E.A., Mack, G.A., Jain, V.K., and Madden, J.A. Computer-assisted liver-mass estimation from gamma-camera images. [/sup 99m/Tc-sulfur colloid imaging]. United States: N. p., 1979. Web.
Eikman, E.A., Mack, G.A., Jain, V.K., & Madden, J.A. Computer-assisted liver-mass estimation from gamma-camera images. [/sup 99m/Tc-sulfur colloid imaging]. United States.
Eikman, E.A., Mack, G.A., Jain, V.K., and Madden, J.A. Thu . "Computer-assisted liver-mass estimation from gamma-camera images. [/sup 99m/Tc-sulfur colloid imaging]". United States.
@article{osti_6165496,
title = {Computer-assisted liver-mass estimation from gamma-camera images. [/sup 99m/Tc-sulfur colloid imaging]},
author = {Eikman, E.A. and Mack, G.A. and Jain, V.K. and Madden, J.A.},
abstractNote = {We have devised a computer-assisted method for objective estimation of liver mass from the right lateral projection of radiocolloid images of the liver. Gamma-camera images were digitized, preprocessed, and stored in computer memory. The definition of liver for area measurement was adaptively determined by means of a Laplacian operator that measures change in radioactivity slope associated with the liver margin. Individual thresholds were calculated for each of 16 subregions. A liver-mass index was derived from a linear regression model correlating the area of the right lateral projection with liver weight at autopsy in 50 patients whose livers weighed between 0.8 to 3.0 Kg. The correlation coefficient found for this method was 0.83 using the equation: Liver Mass (kg) = Area (cm/sup 2/)/275 (kg/cm/sup 2/) - 0.215 (kg). Liver-mass estimates using an alternative computer-assisted method or representative manual methods adapted for gamma-camera images showed lower correlation with liver weight at autopsy.},
doi = {},
journal = {J. Nucl. Med.; (United States)},
number = ,
volume = 20:2,
place = {United States},
year = {1979},
month = {2}
}