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Title: Radiation in multidisciplinary treatment of children with malignant ovarian tumors

Abstract

Thirteen girls with malignant ovarian tumors treated at Memorial Hospital fromm August 1971 through October 1975 with extensive surgery, multi-drug chemotherapy (T-2 protocol) and postoperative radiation were reviewed. The plan of radiation was to deliver 3,000 rads to the whole abdomen and boost the para-aortic and pelvic area with 1,500 rads in five to six weeks. In only two patients was the radiation conducted as planned. In others the treatment was either interrupted or discontinued due to complications. Four of the thirteen patients are dead. The cause of death in two of these patients was distant metastases; the two other patients died without evidence of tumor due to treatment complications. Three of the nine patients who are alive without evidence of disease have late complications. Following radical surgery, lower doses of radiation given concomitantly with T-2 protocol chemotherapy seem to be sufficient for controlling the disease.

Authors:
; ;
Publication Date:
Research Org.:
Memorial Sloan-Kettering Cancer Center, New York
OSTI Identifier:
6137950
Resource Type:
Journal Article
Journal Name:
Cancer; (United States)
Additional Journal Information:
Journal Volume: 43:3; Conference: New Orleans, LA, USA, April 26--30, 1978; Other Information: 60. annual meeting of the American Radium society
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; OVARIES; NEOPLASMS; RADIOTHERAPY; SIDE EFFECTS; CHEMOTHERAPY; CHILDREN; EXPERIMENTAL DATA; GRAPHS; ISOLATED VALUES; RADIATION DOSES; SURGERY; SURVIVAL TIME; ANIMALS; BODY; DATA; DATA FORMS; DISEASES; DOSES; FEMALE GENITALS; GONADS; INFORMATION; MAMMALS; MAN; MEDICINE; NUCLEAR MEDICINE; NUMERICAL DATA; ORGANS; PRIMATES; RADIOLOGY; THERAPY; VERTEBRATES; 560151* - Radiation Effects on Animals- Man

Citation Formats

Jereb, B, Wollner, N, and Exelby, P. Radiation in multidisciplinary treatment of children with malignant ovarian tumors. United States: N. p., 1979. Web. doi:10.1002/1097-0142(197903)43:3<1037::AID-CNCR2820430338>3.0.CO;2-N.
Jereb, B, Wollner, N, & Exelby, P. Radiation in multidisciplinary treatment of children with malignant ovarian tumors. United States. https://doi.org/10.1002/1097-0142(197903)43:3<1037::AID-CNCR2820430338>3.0.CO;2-N
Jereb, B, Wollner, N, and Exelby, P. 1979. "Radiation in multidisciplinary treatment of children with malignant ovarian tumors". United States. https://doi.org/10.1002/1097-0142(197903)43:3<1037::AID-CNCR2820430338>3.0.CO;2-N.
@article{osti_6137950,
title = {Radiation in multidisciplinary treatment of children with malignant ovarian tumors},
author = {Jereb, B and Wollner, N and Exelby, P},
abstractNote = {Thirteen girls with malignant ovarian tumors treated at Memorial Hospital fromm August 1971 through October 1975 with extensive surgery, multi-drug chemotherapy (T-2 protocol) and postoperative radiation were reviewed. The plan of radiation was to deliver 3,000 rads to the whole abdomen and boost the para-aortic and pelvic area with 1,500 rads in five to six weeks. In only two patients was the radiation conducted as planned. In others the treatment was either interrupted or discontinued due to complications. Four of the thirteen patients are dead. The cause of death in two of these patients was distant metastases; the two other patients died without evidence of tumor due to treatment complications. Three of the nine patients who are alive without evidence of disease have late complications. Following radical surgery, lower doses of radiation given concomitantly with T-2 protocol chemotherapy seem to be sufficient for controlling the disease.},
doi = {10.1002/1097-0142(197903)43:3<1037::AID-CNCR2820430338>3.0.CO;2-N},
url = {https://www.osti.gov/biblio/6137950}, journal = {Cancer; (United States)},
number = ,
volume = 43:3,
place = {United States},
year = {Thu Mar 01 00:00:00 EST 1979},
month = {Thu Mar 01 00:00:00 EST 1979}
}