Effect of computed tomography noise and tissue heterogeneity on cerebral blood flow determination by xenon-enhanced computed tomography
Journal Article
·
· Med. Phys.; (United States)
The errors associated with derivation of cerebral blood flow values by the xenon-enhanced computed tomography (CT) method have been evaluated as a function of tissue heterogeneity and CT noise. The results of this study indicate that CT noise introduces large errors in the derived flow value when data for a single, unprocessed voxel are used for this purpose. CT noise increases the derived flow values in a systematic way. Tissue heterogeneity results in a systematic error which lowers the derived flow values. Errors due to both parameters are computed for typical and extreme conditions.
- Research Organization:
- Univ. of Pittsburgh, PA
- OSTI ID:
- 6124965
- Journal Information:
- Med. Phys.; (United States), Vol. 14:4
- Country of Publication:
- United States
- Language:
- English
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