Palladium-109 labeled anti-melanoma monoclonal antibodies

Patent · Mon Apr 30 00:00:00 EDT 1984

OSTI ID:6110979

Srivastava, S C; Fawwaz, R A; Ferrone, S

The invention consists of new monoclonal antibodies labelled with Palladium 109, a beta-emitting radionuclide, the method of preparing this material, and its use in the radiotherapy of melanoma. The antibodies are chelate-conjugated and demonstrate a high uptake in melanomas. (ACR)

• DOE Contract Number: AC02-76CH00016
• Assignee: Dept. of Energy
• Application Number: ON: TI85006017
• OSTI ID: 6110979
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
MELANOMAS
RADIOTHERAPY
MONOCLONAL ANTIBODIES
CHEMICAL PREPARATION
BIOLOGICAL LOCALIZATION
CHELATES
LABELLED COMPOUNDS
PALLADIUM 109
UPTAKE
ANTIBODIES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
COMPLEXES
DISEASES
EVEN-ODD NUCLEI
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MEDICINE
MINUTES LIVING RADIOISOTOPES
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
PALLADIUM ISOTOPES
RADIOISOTOPES
RADIOLOGY
SYNTHESIS
THERAPY
550604* - Medicine- Unsealed Radionuclides in Therapy- (1980-)