Urinary delta-aminolevulinic acid (ALA) excretion in humans and cattle as an index of exposure to lead
Disposable ion-exchange chromatographic columns were used to determine delta-aminolevulinic acid (ALA) concentrations in 11 bovine and 184 human urine samples. The mean urinary ALA concentrations in persons working as battery chargers, autopainters, automechanics, and urban first-grade pupils were 11.61 +/- 14.23, 6.51 +/- 3.31, 6.48 +/- 3.36, and 5.71 +/- 2.91 micrograms/ml respectively. These values were higher than those found in urine from gasoline station attendants, university students and laboratory assistants, rural adult farmers, and rural first-grade pupils, which were 4.90 +/- 1.95, 4.93 +/- 1.76, 4.40 +/- 1.79 and 4.51 +/- 2.65 micrograms/ml respectively. In cattle (Holstein Friesian/White Fulani cross) the mean urinary ALA concentration was 1.84 +/- 0.04 micron/ml. The data indicates that persons working around automobile, lead batteries and leaded gasoline had elevated ALA concentrations in urine. Rural humans and cattle did not have significant elevations of urinary ALA.
- OSTI ID:
- 6010386
- Journal Information:
- Vet. Hum. Toxicol.; (United States), Vol. 22:6
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
AMINOLEVULINIC ACID
EXCRETION
LEAD
BIOLOGICAL INDICATORS
ADULTS
CATTLE
CHILDREN
GASOLINE SERVICE STATIONS
HUMAN POPULATIONS
ION EXCHANGE CHROMATOGRAPHY
LEAD-ACID BATTERIES
MAN
PERSONNEL
RURAL AREAS
URBAN AREAS
URINE
AGE GROUPS
AMINO ACIDS
ANIMALS
BIOLOGICAL MATERIALS
BIOLOGICAL WASTES
BODY FLUIDS
CARBOXYLIC ACIDS
CHROMATOGRAPHY
CLEARANCE
COMMERCIAL SECTOR
DOMESTIC ANIMALS
ELECTRIC BATTERIES
ELECTROCHEMICAL CELLS
ELEMENTS
MAMMALS
MARKETERS
MATERIALS
METALS
ORGANIC ACIDS
ORGANIC COMPOUNDS
POPULATIONS
PRIMATES
RETAILERS
RUMINANTS
SEPARATION PROCESSES
VERTEBRATES
WASTES
560306* - Chemicals Metabolism & Toxicology- Man- (-1987)
560305 - Chemicals Metabolism & Toxicology- Vertebrates- (-1987)