High surface area catalysts for H/sub 2/ reduction of an enzyme: reduction of NAD/sup +/ to NADH
Journal Article
·
· J. Am. Chem. Soc.; (United States)
This paper describes the catalytic reduction of NAD/sup +/ using a pyridine-derived redox polymer and H/sub 2/. The enzymes formate dehydrogenase or lipamide dehydrogenase have been used to mediate the reaction; a platinum catalyst is also required to activate molecular H/sub 2/. The redox polymer, designated (PQ/sup 2 +/ x pt)/sub n/ was anchored on high surface area SiO/sub 2/. The system is presented as a viable means of equilibrating the H/sub 2/O/H/sub 2/ redox system with catalytically active redox enzymes, thus establishing the viability of using H/sub 2/ as a reductant in enzymatic processes.
- Research Organization:
- Massachusetts Institute of Technology, Cambridge
- OSTI ID:
- 5999063
- Journal Information:
- J. Am. Chem. Soc.; (United States), Vol. 109:19
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
59 BASIC BIOLOGICAL SCIENCES
NAD
REDUCTION
PYRIDINES
CATALYTIC EFFECTS
DIAPHORASE
ENZYME ACTIVITY
EQUILIBRIUM
HYDROGEN
OXIDOREDUCTASES
PLATINUM
POLYMERS
SILICON OXIDES
SURFACE AREA
AZINES
CHALCOGENIDES
CHEMICAL REACTIONS
COENZYMES
ELEMENTS
ENZYMES
HETEROCYCLIC COMPOUNDS
ISOALLOXAZINES
METALS
NONMETALS
NUCLEOTIDE DEHYDROGENASES
NUCLEOTIDES
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
OXIDES
OXYGEN COMPOUNDS
PLATINUM METALS
SILICON COMPOUNDS
SURFACE PROPERTIES
TRANSITION ELEMENTS
550200* - Biochemistry
NAD
REDUCTION
PYRIDINES
CATALYTIC EFFECTS
DIAPHORASE
ENZYME ACTIVITY
EQUILIBRIUM
HYDROGEN
OXIDOREDUCTASES
PLATINUM
POLYMERS
SILICON OXIDES
SURFACE AREA
AZINES
CHALCOGENIDES
CHEMICAL REACTIONS
COENZYMES
ELEMENTS
ENZYMES
HETEROCYCLIC COMPOUNDS
ISOALLOXAZINES
METALS
NONMETALS
NUCLEOTIDE DEHYDROGENASES
NUCLEOTIDES
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
OXIDES
OXYGEN COMPOUNDS
PLATINUM METALS
SILICON COMPOUNDS
SURFACE PROPERTIES
TRANSITION ELEMENTS
550200* - Biochemistry