Bone marrow ablation followed by allogeneic marrow grafting during first complete remission of acute nonlymphocytic leukemia

Journal Article · Tue Mar 01 00:00:00 EST 1983 · Blood; (United States)

OSTI ID:5995347

Forman, S J; Spruce, W E; Farbstein, M J

Of 33 patients who had undergone allogeneic bone marrow transplantation during first complete remission of acute nonlymphocytic leukemia, 21 patients have now been followed in continued complete remission for 6-64 mo (median greater than 18 mo) without maintenance chemotherapy. The median age of the surviving patients is 27 yr. Transplant-related complications occurring throughout the first year after marrow grafting were fatal in 7 patients, and leukemic recurrence led to the death of 5 patients. The actuarial long-term disease-free survival is 60% and the actuarial remission rate is 79%.

• Research Organization: Department of Hematology and BMT, City of Hope National Medical Center, Duarte, CA
• OSTI ID: 5995347
• Journal Information: Blood; (United States), Vol. 61:3
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BONE MARROW
BIOLOGICAL RADIATION EFFECTS
TRANSPLANTS
LEUKEMIA
CHEMOTHERAPY
RADIOTHERAPY
BONE MARROW CELLS
PATIENTS
SURVIVAL TIME
WHOLE-BODY IRRADIATION
ANIMAL CELLS
ANIMAL TISSUES
BIOLOGICAL EFFECTS
BODY
CONNECTIVE TISSUE CELLS
DISEASES
EXTERNAL IRRADIATION
HEMATOPOIETIC SYSTEM
HEMIC DISEASES
IRRADIATION
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
RADIATION EFFECTS
RADIOLOGY
SOMATIC CELLS
THERAPY
TISSUES
550603* - Medicine- External Radiation in Therapy- (1980-)
560151 - Radiation Effects on Animals- Man