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Title: Peroxidation of the dried thin film of lipid by high-energy alpha particles from a cyclotron

Abstract

High-energy ..cap alpha.. particles produced a dose-dependent linear increase in different lipid peroxidation products (e.g., malondialdehyde (MDA), conjugated dienes, and hydroperoxides) in the dried thin film state. An inverse dose-rate effect was observed when the dose rate was varied by changing either the ..cap alpha..-particle fluence rate or the ..cap alpha..-particle energy. The antioxidants ..cap alpha..-tocopherol and butylated hydroxytoluene (BHT) suppressed the ..cap alpha..-particle-induced lipid peroxidation in the dried thin film state, and in this respect ..cap alpha..-tocopherol was found superior to BHT. It was found that ..cap alpha..-tocopherol was equally efficient in inhibiting lipid peroxidations by ..cap alpha.. particles and ultraviolet light.

Authors:
;
Publication Date:
Research Org.:
Saha Inst. of Nuclear Physics, Calcutta, India
OSTI Identifier:
5993661
Resource Type:
Journal Article
Journal Name:
Radiat. Res.; (United States)
Additional Journal Information:
Journal Volume: 100:2
Country of Publication:
United States
Language:
English
Subject:
38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY; LIPIDS; CHEMICAL RADIATION EFFECTS; ALPHA PARTICLES; ANTIOXIDANTS; DOSE-RESPONSE RELATIONSHIPS; EXPERIMENTAL DATA; EXTREME ULTRAVIOLET RADIATION; LECITHINS; PEROXIDES; VARIABLE ENERGY CYCLOTRONS; ACCELERATORS; CHARGED PARTICLES; CHEMISTRY; CYCLIC ACCELERATORS; CYCLOTRONS; DATA; ELECTROMAGNETIC RADIATION; ESTERS; INFORMATION; NUMERICAL DATA; ORGANIC COMPOUNDS; ORGANIC PHOSPHORUS COMPOUNDS; OXYGEN COMPOUNDS; PHOSPHOLIPIDS; RADIATION CHEMISTRY; RADIATION EFFECTS; RADIATIONS; ULTRAVIOLET RADIATION; 400600* - Radiation Chemistry

Citation Formats

Agarwal, S, and Chatterjee, S N. Peroxidation of the dried thin film of lipid by high-energy alpha particles from a cyclotron. United States: N. p., 1984. Web. doi:10.2307/3576346.
Agarwal, S, & Chatterjee, S N. Peroxidation of the dried thin film of lipid by high-energy alpha particles from a cyclotron. United States. https://doi.org/10.2307/3576346
Agarwal, S, and Chatterjee, S N. 1984. "Peroxidation of the dried thin film of lipid by high-energy alpha particles from a cyclotron". United States. https://doi.org/10.2307/3576346.
@article{osti_5993661,
title = {Peroxidation of the dried thin film of lipid by high-energy alpha particles from a cyclotron},
author = {Agarwal, S and Chatterjee, S N},
abstractNote = {High-energy ..cap alpha.. particles produced a dose-dependent linear increase in different lipid peroxidation products (e.g., malondialdehyde (MDA), conjugated dienes, and hydroperoxides) in the dried thin film state. An inverse dose-rate effect was observed when the dose rate was varied by changing either the ..cap alpha..-particle fluence rate or the ..cap alpha..-particle energy. The antioxidants ..cap alpha..-tocopherol and butylated hydroxytoluene (BHT) suppressed the ..cap alpha..-particle-induced lipid peroxidation in the dried thin film state, and in this respect ..cap alpha..-tocopherol was found superior to BHT. It was found that ..cap alpha..-tocopherol was equally efficient in inhibiting lipid peroxidations by ..cap alpha.. particles and ultraviolet light.},
doi = {10.2307/3576346},
url = {https://www.osti.gov/biblio/5993661}, journal = {Radiat. Res.; (United States)},
number = ,
volume = 100:2,
place = {United States},
year = {Thu Nov 01 00:00:00 EST 1984},
month = {Thu Nov 01 00:00:00 EST 1984}
}