Use of radiologic modalities in coccidioidal meningitis
The diagnostic utility of pentetate indium trisodium CSF studies, technetium Tc 99m brain scans, and computerized tomographic (CT) scans was evaluated in eight patients in whom coccidioidal meningitis developed following a dust storm in the Central Valley of California. The 111In flow studies and the CT scans demonstrated hydrocephalus in five patients with clinical findings suggesting this complication. Ventriculitis has not previously been diagnosed before death in patients with coccidioidal meningitis; however, it was demonstrated in two patients by the technetium Tc 99m brain scan. The finding that communicating hydrocephalus occurs early in meningitis and interferes with CSF flow into infected basilar regions has important therapeutic implications in that antifungal agents injected into the lumbar subarachnoid space may not reach these regions.
- OSTI ID:
- 5942606
- Journal Information:
- Arch. Intern. Med.; (United States), Vol. 141:1
- Country of Publication:
- United States
- Language:
- English
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MENINGES
TECHNETIUM 99
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ISOMERIC NUCLEI
PATIENTS
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BETA-MINUS DECAY RADIOISOTOPES
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INDIUM ISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
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MINUTES LIVING RADIOISOTOPES
NERVOUS SYSTEM
NUCLEI
ODD-EVEN NUCLEI
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TECHNETIUM ISOTOPES
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550601* - Medicine- Unsealed Radionuclides in Diagnostics