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Title: Cerebral blood flow in humans following resuscitation from cardiac arrest

Abstract

Cerebral blood flow was measured by xenon-133 washout in 13 patients 6-46 hours after being resuscitated from cardiac arrest. Patients regaining consciousness had relatively normal cerebral blood flow before regaining consciousness, but all patients who died without regaining consciousness had increased cerebral blood flow that appeared within 24 hours after resuscitation (except in one patient in whom the first measurement was delayed until 28 hours after resuscitation, by which time cerebral blood flow was increased). The cause of the delayed-onset increase in cerebral blood flow is not known, but the increase may have adverse effects on brain function and may indicate the onset of irreversible brain damage.

Authors:
; ; ; ; ;
Publication Date:
Research Org.:
Georgetown Univ. School of Medicine, Washington, DC (USA)
OSTI Identifier:
5931958
Resource Type:
Journal Article
Resource Relation:
Journal Name: Stroke; (United States); Journal Volume: 20:6
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BRAIN; EMISSION COMPUTED TOMOGRAPHY; CEREBRAL CORTEX; BLOOD FLOW; ISCHEMIA; DIAGNOSIS; HEART; PATIENTS; XENON 132; BODY; CARDIOVASCULAR DISEASES; CARDIOVASCULAR SYSTEM; CENTRAL NERVOUS SYSTEM; CEREBRUM; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; DISEASES; EVEN-EVEN NUCLEI; EVEN-ODD NUCLEI; INTERMEDIATE MASS NUCLEI; ISOTOPES; NERVOUS SYSTEM; NUCLEI; ORGANS; STABLE ISOTOPES; TOMOGRAPHY; VASCULAR DISEASES; XENON ISOTOPES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics

Citation Formats

Cohan, S.L., Mun, S.K., Petite, J., Correia, J., Tavelra Da Silva, A.T., and Waldhorn, R.E. Cerebral blood flow in humans following resuscitation from cardiac arrest. United States: N. p., 1989. Web. doi:10.1161/01.STR.20.6.761.
Cohan, S.L., Mun, S.K., Petite, J., Correia, J., Tavelra Da Silva, A.T., & Waldhorn, R.E. Cerebral blood flow in humans following resuscitation from cardiac arrest. United States. doi:10.1161/01.STR.20.6.761.
Cohan, S.L., Mun, S.K., Petite, J., Correia, J., Tavelra Da Silva, A.T., and Waldhorn, R.E. Thu . "Cerebral blood flow in humans following resuscitation from cardiac arrest". United States. doi:10.1161/01.STR.20.6.761.
@article{osti_5931958,
title = {Cerebral blood flow in humans following resuscitation from cardiac arrest},
author = {Cohan, S.L. and Mun, S.K. and Petite, J. and Correia, J. and Tavelra Da Silva, A.T. and Waldhorn, R.E.},
abstractNote = {Cerebral blood flow was measured by xenon-133 washout in 13 patients 6-46 hours after being resuscitated from cardiac arrest. Patients regaining consciousness had relatively normal cerebral blood flow before regaining consciousness, but all patients who died without regaining consciousness had increased cerebral blood flow that appeared within 24 hours after resuscitation (except in one patient in whom the first measurement was delayed until 28 hours after resuscitation, by which time cerebral blood flow was increased). The cause of the delayed-onset increase in cerebral blood flow is not known, but the increase may have adverse effects on brain function and may indicate the onset of irreversible brain damage.},
doi = {10.1161/01.STR.20.6.761},
journal = {Stroke; (United States)},
number = ,
volume = 20:6,
place = {United States},
year = {Thu Jun 01 00:00:00 EDT 1989},
month = {Thu Jun 01 00:00:00 EDT 1989}
}