Cerebral blood flow in humans following resuscitation from cardiac arrest
Cerebral blood flow was measured by xenon-133 washout in 13 patients 6-46 hours after being resuscitated from cardiac arrest. Patients regaining consciousness had relatively normal cerebral blood flow before regaining consciousness, but all patients who died without regaining consciousness had increased cerebral blood flow that appeared within 24 hours after resuscitation (except in one patient in whom the first measurement was delayed until 28 hours after resuscitation, by which time cerebral blood flow was increased). The cause of the delayed-onset increase in cerebral blood flow is not known, but the increase may have adverse effects on brain function and may indicate the onset of irreversible brain damage.
- Research Organization:
- Georgetown Univ. School of Medicine, Washington, DC (USA)
- OSTI ID:
- 5931958
- Journal Information:
- Stroke; (United States), Vol. 20:6
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
BRAIN
EMISSION COMPUTED TOMOGRAPHY
CEREBRAL CORTEX
BLOOD FLOW
ISCHEMIA
DIAGNOSIS
HEART
PATIENTS
XENON 132
BODY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
CENTRAL NERVOUS SYSTEM
CEREBRUM
COMPUTERIZED TOMOGRAPHY
DIAGNOSTIC TECHNIQUES
DISEASES
EVEN-EVEN NUCLEI
EVEN-ODD NUCLEI
INTERMEDIATE MASS NUCLEI
ISOTOPES
NERVOUS SYSTEM
NUCLEI
ORGANS
STABLE ISOTOPES
TOMOGRAPHY
VASCULAR DISEASES
XENON ISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics