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Title: Abnormal epidermal changes after argon laser treatment

Abstract

A 26-year-old woman with a congenital port-wine stain on the forehead was treated three times at 2-month intervals with an argon laser. Six months after the last treatment, moderate blanching and mild scaling confined to the treated area was observed. A biopsy specimen of the treated area revealed a significant decrease in ectatic vessels. However, epidermal changes similar to those of actinic keratosis with disorganized cell layers and marked cytologic abnormalities were seen. Analysis of peripheral blood lymphocytes for a defect in DNA repair was negative. Multiple, argon laser-induced photothermal effects may be responsible for the changes observed in our case and may lead to premalignant epidermal transformation.

Authors:
; ; ; ; ;  [1]
  1. (Univ. of Vienna (Austria))
Publication Date:
OSTI Identifier:
5921830
Resource Type:
Journal Article
Resource Relation:
Journal Name: Journal of the American Academy of Dermatology; (USA); Journal Volume: 24:2 Pt 2
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; EPIDERMIS; MORPHOLOGICAL CHANGES; LASER RADIATION; BIOLOGICAL EFFECTS; BIOPSY; DNA REPAIR; GAS LASERS; LYMPHOCYTES; ANIMAL CELLS; ANIMAL TISSUES; BIOLOGICAL MATERIALS; BIOLOGICAL RECOVERY; BIOLOGICAL REPAIR; BLOOD; BLOOD CELLS; BODY; BODY FLUIDS; CONNECTIVE TISSUE CELLS; DIAGNOSTIC TECHNIQUES; ELECTROMAGNETIC RADIATION; EPITHELIUM; LASERS; LEUKOCYTES; MATERIALS; ORGANS; RADIATIONS; RECOVERY; REPAIR; SKIN; SOMATIC CELLS; TISSUES; 560400* - Other Environmental Pollutant Effects

Citation Formats

Neumann, R.A., Knobler, R.M., Aberer, E., Klein, W., Kocsis, F., and Ott, E. Abnormal epidermal changes after argon laser treatment. United States: N. p., 1991. Web. doi:10.1016/0190-9622(91)70055-7.
Neumann, R.A., Knobler, R.M., Aberer, E., Klein, W., Kocsis, F., & Ott, E. Abnormal epidermal changes after argon laser treatment. United States. doi:10.1016/0190-9622(91)70055-7.
Neumann, R.A., Knobler, R.M., Aberer, E., Klein, W., Kocsis, F., and Ott, E. 1991. "Abnormal epidermal changes after argon laser treatment". United States. doi:10.1016/0190-9622(91)70055-7.
@article{osti_5921830,
title = {Abnormal epidermal changes after argon laser treatment},
author = {Neumann, R.A. and Knobler, R.M. and Aberer, E. and Klein, W. and Kocsis, F. and Ott, E.},
abstractNote = {A 26-year-old woman with a congenital port-wine stain on the forehead was treated three times at 2-month intervals with an argon laser. Six months after the last treatment, moderate blanching and mild scaling confined to the treated area was observed. A biopsy specimen of the treated area revealed a significant decrease in ectatic vessels. However, epidermal changes similar to those of actinic keratosis with disorganized cell layers and marked cytologic abnormalities were seen. Analysis of peripheral blood lymphocytes for a defect in DNA repair was negative. Multiple, argon laser-induced photothermal effects may be responsible for the changes observed in our case and may lead to premalignant epidermal transformation.},
doi = {10.1016/0190-9622(91)70055-7},
journal = {Journal of the American Academy of Dermatology; (USA)},
number = ,
volume = 24:2 Pt 2,
place = {United States},
year = 1991,
month = 2
}