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Title: A practical method for incorporating scatter in a projector-backprojector for accurate scatter compensation in SPECT

Abstract

A projector-backprojector pair has been developed that models attenuation and the spatially variant collimator and scatter response functions in a uniformly attenuating object for single photon emission computed tomography (SPECT). In particular, the scatter response function (SRF) is modeled using a scheme based on the scatter responses of point sources in a large slab phantom. This scheme, slab derived scatter estimation, allows efficient and accurate modeling of the asymmetric and spatially variant properties of the scatter response during the projection and backprojection operations. The scatter model has been verified by comparison of scatter line source response functions, scatter/primary ratios, and projection data from extended source distributions obtained using this method and direct Monte Carlo (MC) simulations. It eliminates the need for extensive MC simulations for each object imaged and the extremely large memory required to store the resulting SRF's for every pixel and view during the projection and backprojection process. While the computational requirements of this method are substantial, they are significantly less than those required for MC simulations. Combined with iterative reconstruction techniques, this projector-backprojector provides a practical and accurate means for scatter compensation in SPECT. Preliminary results of combining this projector-backprojector with the maximum likelihood-expectation maximization algorithm showmore » a significant increase in quantitative accuracy as compared to compensation for only attenuation and the spatially variant collimator response function.« less

Authors:
;  [1]
  1. Univ. of North Carolina, Chapel Hill, NC (United States)
Publication Date:
OSTI Identifier:
5895582
Resource Type:
Journal Article
Journal Name:
IEEE Transactions on Nuclear Science (Institute of Electrical and Electronics Engineers); (United States)
Additional Journal Information:
Journal Volume: 40:4 part 1; Journal ID: ISSN 0018-9499
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY; SCATTERING; ACCURACY; ATTENUATION; MATHEMATICAL MODELS; MONTE CARLO METHOD; CALCULATION METHODS; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; EMISSION COMPUTED TOMOGRAPHY; TOMOGRAPHY; 550601* - Medicine- Unsealed Radionuclides in Diagnostics

Citation Formats

Frey, E C, and Tsui, B M.W. A practical method for incorporating scatter in a projector-backprojector for accurate scatter compensation in SPECT. United States: N. p., 1993. Web. doi:10.1109/23.256720.
Frey, E C, & Tsui, B M.W. A practical method for incorporating scatter in a projector-backprojector for accurate scatter compensation in SPECT. United States. https://doi.org/10.1109/23.256720
Frey, E C, and Tsui, B M.W. 1993. "A practical method for incorporating scatter in a projector-backprojector for accurate scatter compensation in SPECT". United States. https://doi.org/10.1109/23.256720.
@article{osti_5895582,
title = {A practical method for incorporating scatter in a projector-backprojector for accurate scatter compensation in SPECT},
author = {Frey, E C and Tsui, B M.W.},
abstractNote = {A projector-backprojector pair has been developed that models attenuation and the spatially variant collimator and scatter response functions in a uniformly attenuating object for single photon emission computed tomography (SPECT). In particular, the scatter response function (SRF) is modeled using a scheme based on the scatter responses of point sources in a large slab phantom. This scheme, slab derived scatter estimation, allows efficient and accurate modeling of the asymmetric and spatially variant properties of the scatter response during the projection and backprojection operations. The scatter model has been verified by comparison of scatter line source response functions, scatter/primary ratios, and projection data from extended source distributions obtained using this method and direct Monte Carlo (MC) simulations. It eliminates the need for extensive MC simulations for each object imaged and the extremely large memory required to store the resulting SRF's for every pixel and view during the projection and backprojection process. While the computational requirements of this method are substantial, they are significantly less than those required for MC simulations. Combined with iterative reconstruction techniques, this projector-backprojector provides a practical and accurate means for scatter compensation in SPECT. Preliminary results of combining this projector-backprojector with the maximum likelihood-expectation maximization algorithm show a significant increase in quantitative accuracy as compared to compensation for only attenuation and the spatially variant collimator response function.},
doi = {10.1109/23.256720},
url = {https://www.osti.gov/biblio/5895582}, journal = {IEEE Transactions on Nuclear Science (Institute of Electrical and Electronics Engineers); (United States)},
issn = {0018-9499},
number = ,
volume = 40:4 part 1,
place = {United States},
year = {Sun Aug 01 00:00:00 EDT 1993},
month = {Sun Aug 01 00:00:00 EDT 1993}
}