Immunoreactive luteinizing hormone-releasing hormone in the seminal plasma and human semen parameters
A luteinizing hormone-releasing hormone (LH-RH)-like substance has been detected in human seminal plasma by a radioimmunoassay (RIA) with a highly specific anti-LH-RH antiserum. The seminal samples - not only the plasma itself but also the sample extracted by an acid/alcohol method - showed satisfactory displacement curves in our RIA system. The relationship between fertility and the LH-RH values in the seminal plasma was studied by comparing the peptide levels with sperm concentration and motility. By these two parameters, 103 samples were divided into four groups. In the low-concentration groups (oligozoospermic patients), the hormonal concentrations differed significantly between those specimens demonstrating good and poor motility. These data suggest that this immunoreactive LH-RH may play a role in human spermatogenesis.
- Research Organization:
- Keio Univ., Tokyo, Japan
- OSTI ID:
- 5880664
- Journal Information:
- Fert. Steril.; (United States), Vol. 43:4
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
59 BASIC BIOLOGICAL SCIENCES
LH-RH
RADIOIMMUNOASSAY
REPRODUCTIVE DISORDERS
DIAGNOSIS
BODY FLUIDS
FERTILITY
MALE GENITALS
PATIENTS
SPERMATOGENESIS
BIOLOGICAL MATERIALS
BODY
GAMETOGENESIS
HORMONES
IMMUNOASSAY
IMMUNOLOGY
ISOTOPE APPLICATIONS
LIBERINS
MATERIALS
ORGANS
PEPTIDE HORMONES
PITUITARY HORMONES
RADIOASSAY
RADIOIMMUNOLOGY
TRACER TECHNIQUES
550601* - Medicine- Unsealed Radionuclides in Diagnostics
551001 - Physiological Systems- Tracer Techniques