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Title: /ital In/ /ital vivo/ measurement of cortical bone lead using polarized x rays

Abstract

An x-ray fluorescence system which utilizes polarized radiation to measure lead in vivo in human subjects is described. The minimum detection limit is approximately 6.4 ppm wet weight lead in the cortex of the tibia with 4 mm of overlying soft tissue. This appears to be adequate for assessing lead stores in lead-toxic preschool children. The measurement requires 16.5 min and is associated with an effective equivalent whole body dose to the subject of 2.5 /mu/Sv. The system, its calibration and its validation are described herein.

Authors:
; ; ; ;
Publication Date:
Research Org.:
Radiation Oncology Department, University Hospital at Stony Brook, State University of New York, Stony Brook, New York 11794-7028(US); Department of Pediatrics, Albert Einstein College of Medicine of Yeshiva University, Montefiore Medical Center, Bronx, New York 10467-2490; Medical Department, Brookhaven National Laboratory, Upton, New York 11973; Biology Department, Tsinghua University, Beijing, People's Republic of China
OSTI Identifier:
5877148
Resource Type:
Journal Article
Journal Name:
Med. Phys.; (United States)
Additional Journal Information:
Journal Volume: 16:4
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; BONE TISSUES; BIOMEDICAL RADIOGRAPHY; CHILDREN; SCREENING; LEAD; TOXICITY; FLUORESCENCE; IN VIVO; X-RAY RADIOGRAPHY; AGE GROUPS; ANIMAL TISSUES; BODY; CONNECTIVE TISSUE; DIAGNOSTIC TECHNIQUES; ELEMENTS; INDUSTRIAL RADIOGRAPHY; LUMINESCENCE; MEDICINE; METALS; NUCLEAR MEDICINE; RADIOLOGY; TISSUES; 560300* - Chemicals Metabolism & Toxicology

Citation Formats

Wielopolski, L, Rosen, J F, Slatkin, D N, Zhang, R, and Kalef-Ezra, J A. /ital In/ /ital vivo/ measurement of cortical bone lead using polarized x rays. United States: N. p., 1989. Web.
Wielopolski, L, Rosen, J F, Slatkin, D N, Zhang, R, & Kalef-Ezra, J A. /ital In/ /ital vivo/ measurement of cortical bone lead using polarized x rays. United States.
Wielopolski, L, Rosen, J F, Slatkin, D N, Zhang, R, and Kalef-Ezra, J A. 1989. "/ital In/ /ital vivo/ measurement of cortical bone lead using polarized x rays". United States.
@article{osti_5877148,
title = {/ital In/ /ital vivo/ measurement of cortical bone lead using polarized x rays},
author = {Wielopolski, L and Rosen, J F and Slatkin, D N and Zhang, R and Kalef-Ezra, J A},
abstractNote = {An x-ray fluorescence system which utilizes polarized radiation to measure lead in vivo in human subjects is described. The minimum detection limit is approximately 6.4 ppm wet weight lead in the cortex of the tibia with 4 mm of overlying soft tissue. This appears to be adequate for assessing lead stores in lead-toxic preschool children. The measurement requires 16.5 min and is associated with an effective equivalent whole body dose to the subject of 2.5 /mu/Sv. The system, its calibration and its validation are described herein.},
doi = {},
url = {https://www.osti.gov/biblio/5877148}, journal = {Med. Phys.; (United States)},
number = ,
volume = 16:4,
place = {United States},
year = {Sat Jul 01 00:00:00 EDT 1989},
month = {Sat Jul 01 00:00:00 EDT 1989}
}