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Title: Current approaches to the management of internally contaminated persons

Abstract

Appropriate treatment for internal depositions of some radionuclides can reduce the radiation doses by as much as factors of two to ten. While at first thought that may seem a relatively small therapeutic effect, it is a useful gain for the patient in reducing the dose and may be a significant help in preventing late effects from the radiation. The list of important available treatments include agents that reduce gastrointestinal absorption, blocking and diluting compounds, mobilizing agents, and chelating drugs. Wound irrigation or excision and lung lavage are mechanical techniques that can reduce radionuclide depositions. Successful treatment depends on early application of these drugs and techniques following exposure. This must be done usually on the basis of very limited exposure information, which emphasizes the need for preplanning the medical emergency program if internal radioactive contamination is possible. In most cases, the risks of treatment are well identified. Since the exposure risks are often poorly understood when the decision for treatment must be made, the omission of treatment can be more serious than proceeding with a low or no risk therapeutic regimen.

Authors:
Publication Date:
Research Org.:
Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
OSTI Identifier:
5824620
Report Number(s):
LA-UR-79-3054; CONF-791085-2
TRN: 80-002216
DOE Contract Number:  
W-7495-ENG-36
Resource Type:
Conference
Resource Relation:
Conference: Radiation accident preparedness conference, Oak Ridge, TN, USA, 19 Oct 1979
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; PERSONNEL; DECONTAMINATION; POST-IRRADIATION THERAPY; CHELATING AGENTS; DRUGS; RADIOISOTOPES; EXCRETION; INTESTINAL ABSORPTION; REMOVAL; CONTAMINATION; DILUTION; LAVAGE; CLEANING; CLEARANCE; ISOTOPES; THERAPY; UPTAKE; 560171* - Radiation Effects- Nuclide Kinetics & Toxicology- Man- (-1987)

Citation Formats

Voelz, G L. Current approaches to the management of internally contaminated persons. United States: N. p., 1979. Web.
Voelz, G L. Current approaches to the management of internally contaminated persons. United States.
Voelz, G L. 1979. "Current approaches to the management of internally contaminated persons". United States. https://www.osti.gov/servlets/purl/5824620.
@article{osti_5824620,
title = {Current approaches to the management of internally contaminated persons},
author = {Voelz, G L},
abstractNote = {Appropriate treatment for internal depositions of some radionuclides can reduce the radiation doses by as much as factors of two to ten. While at first thought that may seem a relatively small therapeutic effect, it is a useful gain for the patient in reducing the dose and may be a significant help in preventing late effects from the radiation. The list of important available treatments include agents that reduce gastrointestinal absorption, blocking and diluting compounds, mobilizing agents, and chelating drugs. Wound irrigation or excision and lung lavage are mechanical techniques that can reduce radionuclide depositions. Successful treatment depends on early application of these drugs and techniques following exposure. This must be done usually on the basis of very limited exposure information, which emphasizes the need for preplanning the medical emergency program if internal radioactive contamination is possible. In most cases, the risks of treatment are well identified. Since the exposure risks are often poorly understood when the decision for treatment must be made, the omission of treatment can be more serious than proceeding with a low or no risk therapeutic regimen.},
doi = {},
url = {https://www.osti.gov/biblio/5824620}, journal = {},
number = ,
volume = ,
place = {United States},
year = {Fri Sep 28 00:00:00 EDT 1979},
month = {Fri Sep 28 00:00:00 EDT 1979}
}

Conference:
Other availability
Please see Document Availability for additional information on obtaining the full-text document. Library patrons may search WorldCat to identify libraries that hold this conference proceeding.

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