DNA sequences, recombinant DNA molecules and processes for producing bovine growth hormone-like polypeptides in high yield

Patent · Tue Sep 15 00:00:00 EDT 1987

OSTI ID:5823398

Buell, G N

This patent describes a process for increasing the yield of a bovine growth hormone-like polypeptide to at least 100 times that of a bovine growth hormone-like polypeptide encoded by a DNA sequence. The process comprises the steps of culturing a host transformed with a recombinant DNA molecule comprising DNA sequence encoding a Met ..lambda.. or ..lambda.. bovine growth hormone-like polypetide operatively linked to an expression control sequence. The ..lambda.. is an amino terminal deletion from the amino acid sequence of mature bovine growth hormone.

• Assignee: Biogen N.V., Curacao
• Patent Number(s): US 4693973
• Application Number: TRN: 87-040843
• OSTI ID: 5823398
• Resource Relation: Patent File Date: Filed date 11 Aug 1983
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
60 APPLIED LIFE SCIENCES
PEPTIDE HORMONES
CHEMICAL PREPARATION
RECOMBINANT DNA
STH
AMINO ACIDS
ANIMAL GROWTH
CHEMICAL REACTION YIELD
COWS
DNA SEQUENCING
MOLECULES
ANIMALS
CARBOXYLIC ACIDS
CATTLE
DNA
DOMESTIC ANIMALS
GROWTH
HORMONES
MAMMALS
NUCLEIC ACIDS
ORGANIC ACIDS
ORGANIC COMPOUNDS
PITUITARY HORMONES
RUMINANTS
STRUCTURAL CHEMICAL ANALYSIS
SYNTHESIS
VERTEBRATES
YIELDS
550400* - Genetics
553004 - Agriculture & Food Technology- Food Protection & Preservation- (1987-)