Effect of gender on glucose utilization rates in healthy humans: A positron emission tomography study

Journal Article · Sat Dec 01 00:00:00 EST 1990 · Journal of Neuroscience Research; (USA)

DOI:https://doi.org/10.1002/jnr.490270410· OSTI ID:5800975

Miura, S A; Schapiro, M B; Grady, C L; Kumar, A; Salerno, J A; Kozachuk, W E; Wagner, E; Rapoport, S I; Horwitz, B ^[1]

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1. National Institutes of Health, Bethesda, MD (USA)

Positron emission tomography (PET) was used with 18fluorodeoxyglucose to see if gender differences in resting cerebral glucose utilization could be detected. Thirty-two healthy subjects (15 women and 17 men; age range: 21-38 yr) were examined using a high-resolution PET scanner to determine the regional cerebral metabolic rate for glucose (CMRglc) in 65 gray matter regions of interest. Whole brain CMRglc did not differ significantly between the two genders, nor did any of the regional CMRglc values. Only 1 of 65 ratios of regional-to-whole brain CMRglc differed significantly between men and women, which is consistent with chance. These results indicate that there are no differences in resting regional cerebral glucose utilization between young men and women.

• OSTI ID: 5800975
• Journal Information: Journal of Neuroscience Research; (USA), Vol. 27:4; ISSN 0360-4012
• Country of Publication: United States
• Language: English

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BRAIN
POSITRON COMPUTED TOMOGRAPHY
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FLUORINE 18
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ANIMALS
BETA DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
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FLUORINE ISOTOPES
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LIGHT NUCLEI
MAMMALS
MONOSACCHARIDES
NERVOUS SYSTEM
NUCLEI
ODD-ODD NUCLEI
ORGANIC COMPOUNDS
ORGANS
PRIMATES
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SACCHARIDES
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