Relative Biological Effectiveness (RBE) of fission neutrons and gamma rays at occupational exposure levels: Volume 2, Studies on the effects of 60 equal once-weekly exposures to fission neutrons and gamma rays on survival of mice
A total of 6316 mice were exposed to 60 once-weekly doses of 0.85 MeV fission neutrons or /sup 60/Co gamma rays and observed until they died. An additional 1404 mice were entered into the experiment and followed for part of their lifetimes; a few of these mice were lost accidentally, but most were removed for genetic testing. The mean aftersurvival (MAS) times showed dose-response curves for both neutron and gamma-ray exposures to be linear over all doses except the highest neutron dose. The relative biological effectiveness (RBE) value for neutrons, calculated as the ratio of the linear slopes of the dose-response curves for MAS times, was about 20 for both males and females. Essentially the same value was obtained by other analyses of the data. This RBE value of 20 is specific for deaths from all causes after 60 once-weekly exposures to 0.85 MeV fission neutrons, with once-weekly /sup 60/Co gamma-ray exposures as the reference radiation. The value for the RBE will probably be different for some, but not all, of the other end points (i.e., specific causes of death, especially tumors). 21 refs., 6 figs., 6 tabs.
- Research Organization:
- Argonne National Lab., IL (USA)
- DOE Contract Number:
- W-31109-ENG-38
- OSTI ID:
- 5778926
- Report Number(s):
- NUREG/CR-4704-Vol.2; ANL-86-33-Vol.2; ON: TI88003950; TRN: 88-003601
- Country of Publication:
- United States
- Language:
- English
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Relative biological effectiveness (RBE) of fission neutrons and gamma rays at occupational exposure levels: Volume 1, Studies on the genetic effects in mice of 60 equal once-weekly exposures to fission neutrons and gamma rays
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Related Subjects
COBALT 60
RBE
GAMMA RADIATION
NEOPLASMS
RADIOINDUCTION
OCCUPATIONAL EXPOSURE
SIMULATION
CHRONIC EXPOSURE
DOSE-RESPONSE RELATIONSHIPS
FISSION NEUTRONS
LIFE SPAN
LOW DOSE IRRADIATION
MICE
MORTALITY
SURVIVAL TIME
ANIMALS
BARYONS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
COBALT ISOTOPES
DISEASES
ELECTROMAGNETIC RADIATION
ELEMENTARY PARTICLES
FERMIONS
HADRONS
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IONIZING RADIATIONS
IRRADIATION
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MAMMALS
MINUTES LIVING RADIOISOTOPES
NEUTRONS
NUCLEI
NUCLEONS
ODD-ODD NUCLEI
RADIATIONS
RADIOISOTOPES
RODENTS
VERTEBRATES
YEARS LIVING RADIOISOTOPES
560151* - Radiation Effects on Animals- Man