Mortality of 11,500 nickel workers--extended follow up and relationship to environmental conditions

Journal Article · Mon Jul 01 00:00:00 EDT 1991 · Toxicology and Industrial Health; (United States)

DOI:https://doi.org/10.1177/074823379100700404· OSTI ID:5740910

Shannon, H S; Walsh, C; Jadon, N; Julian, J A; Weglo, J K; Thornhill, P G; Cecutti, A G ^[1]

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1. Occupational Health Program, McMaster University, Hamilton, ON (Canada)

An extended follow-up from 1977-84 was achieved in a cohort of 11,567 nickel workers engaged in mining, milling and smelting originally studied from 1950-76. Exposure data were incorporated into the analysis. One nasal cancer occurred. The lung cancer Standardized Mortality Ratio beyond 15 years from first exposure was significantly high overall (128) and in miners (153). However, detailed analyses by era of first mining and duration of mining, as well as cumulative exposure to different nickel species, did not appear consistent with an occupational etiology since significant trends were not observed. At the levels of exposure incurred, large increases in lung and nasal cancer, observed in nickel refineries elsewhere, did not occur.

• OSTI ID: 5740910
• Journal Information: Toxicology and Industrial Health; (United States), Vol. 7:4; ISSN 0748-2337
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
NICKEL
TOXICITY
LUNGS
METALLURGY
MINING
MORTALITY
NEOPLASMS
NOSE
OCCUPATIONAL EXPOSURE
PERSONNEL
BODY
BODY AREAS
DISEASES
ELEMENTS
FACE
HEAD
METALS
ORGANS
RESPIRATORY SYSTEM
TRANSITION ELEMENTS
560300* - Chemicals Metabolism & Toxicology