Oncogenic action of ionizing radiation on rat skin. Comprehensive progress report, February 1, 1984-January 31, 1987

Technical Report · Wed Jan 01 00:00:00 EST 1986

OSTI ID:5687154

Burns, F J

This report describes results from a continuing study predicted on the assumption that a thorough understanding of radiation carcinogenesis in a single organ system is the most productive way to approach a general understanding for radiation carcinogenesis. We have found that a useful model to understand radiation carcinogenesis in rat skin is the, so called, dual action hypothesis. In this initial events resulting in heritable molecular changes are postulated as the starting point for several measurable endpoints or biological damage. 55 refs.

• Research Organization: New York Univ., NY (USA). Medical Center
• DOE Contract Number: AC02-76EV03380
• OSTI ID: 5687154
• Report Number(s): DOE/EV/03380-49; ON: DE86012668
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ONCOGENIC TRANSFORMATIONS
RADIOINDUCTION
BIOLOGICAL REPAIR
CARCINOGENESIS
CELL PROLIFERATION
RADIOBIOLOGY
RATS
SKIN
ANIMALS
BIOLOGICAL RECOVERY
BIOLOGY
BODY
CELL TRANSFORMATIONS
MAMMALS
ORGANS
PATHOGENESIS
RECOVERY
REPAIR
RODENTS
VERTEBRATES
560154* - Radiation Effects on Animals- Basic Studies- (-1987)