The effect of microwave radiation on the stability and formation of gramicidin-A channels in lipid bilayer membranes
- Univ. of Goeteborg (Sweden)
The effects of microwaves on the single-channel kinetics of gramicidin-A channels in lipid bilayer membranes were examined. Attempts were made to separate thermal and athermal effects by accurate measurements of temperature at the site of the membrane and by relating the measured parameters to their previously characterized temperature dependence. It was found that microwave radiation does not affect single-channel conductance or channel life time to a degree that is significantly different from that expected of a purely thermal effect. On the other hand, the rate of channel formation is decreased during exposure, which is opposite to that expected of a purely thermal effect. The mechanism of this effect is discussed in terms of the dimerization process of channel formation.
- OSTI ID:
- 5680422
- Journal Information:
- Bioelectromagnetics (New York); (USA), Vol. 12:1; ISSN 0197-8462
- Country of Publication:
- United States
- Language:
- English
Similar Records
Millimeter microwave effect on ion transport across lipid bilayer membranes
Molecular Mechanism for Gramicidin Dimerization and Dissociation in Bilayers of Different Thickness
Related Subjects
MEMBRANE PROTEINS
BIOSYNTHESIS
MICROWAVE RADIATION
BIOLOGICAL EFFECTS
LIPIDS
TEMPERATURE DEPENDENCE
ELECTROMAGNETIC RADIATION
ORGANIC COMPOUNDS
PROTEINS
RADIATIONS
SYNTHESIS
560400* - Other Environmental Pollutant Effects