Monitoring the response of lymphoma patients to therapy: correlation of abdominal CT findings with clinical course and histologic cell type

Journal Article · Sat Oct 01 00:00:00 EDT 1983 · Radiology; (United States)

DOI:https://doi.org/10.1148/radiology.149.1.6611928· OSTI ID:5653535

Oliver, Jr, T W; Bernardino, M E; Sones, Jr, P J

A review was made of 365 abdominal computed tomographic (CT) examinations in 125 patients with a histologic diagnosis of lymphoma who had undergone CT before and after therapy. Clinical correlation immediately preceding the follow-up CT examination was obtained in 100 patients. In these 100 patients, five distinct subgroups emerged: (a) reduction in extent of disease without changes in internal nodal characteristics; (b) reduction in extent of disease with change in internal nodal characteristics; (c) no change in extent of disease and no change in internal nodal characteristics; (d) no change in extent of disease but change in internal nodal charateristics; and (e) disease progression. Changes in internal nodal architecture consisted of diminished attenuation or mesenteric stranding. A 91% correlation existed between the CT findings and the clinical course. Of those patients with a worsening clinical course, and follow-up CT studies suggesting a stable or improved response to therapy, relapse in the majority (57%) involved the central nervous system. The authors conclude that limited abdominal CT examination is satisfactory in the posttherapy follow-up of lymphoma patients.

• Research Organization: Emory Univ. School of Medicine, Atlanta, GA
• OSTI ID: 5653535
• Journal Information: Radiology; (United States), Vol. 149:1
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
59 BASIC BIOLOGICAL SCIENCES
ABDOMEN
COMPUTERIZED TOMOGRAPHY
PATIENTS
MEDICAL SURVEILLANCE
HISTOLOGY
LYMPHOMAS
BODY
BODY AREAS
DIAGNOSTIC TECHNIQUES
DISEASES
NEOPLASMS
SURVEILLANCE
TOMOGRAPHY
550602* - Medicine- External Radiation in Diagnostics- (1980-)
550900 - Pathology