U.S. Department of EnergyOffice of Scientific and Technical Information
Mass-energy balance for microbial product synthesis--biochemical and cultural aspects
Abstract
Interrelations between the rates of the product synthesis, cell biomass growth, respiration, and organic substrate consumption have been studied by the mass-energy balance method. This method is based on the utilization of a special unit of substance reducity, namely redoxon. Biochemical parameters have been found which are involved in these interrelations and which describe the processes of high-energy bond gain and energy expenditure during metabolism. In order to find these, the separation of the whole metabolism into several partial metabolisms has been applied. Equations have been obtained describing the dependences of the product yield and process specific productivity on the biochemical parameters and two macroscopic rates (e.g., rates of dilution and substrate consumption). Both aerobic and anaerobic product syntheses have been considered. The estimate of the upper limit of process productivity has been obtained. Mechanisms of the influence of the producer's intracellular characteristics on the rates of physiological processes and the culture productivity are discussed.
- Publication Date:
- Research Org.:
- Institute of Biochemistry and Physiology of Microorganisms, USSR Academy of Sciences, 142292 Pushchino, Moscow Region
- OSTI Identifier:
- 5639696
- Resource Type:
- Journal Article
- Journal Name:
- Biotechnol. Bioeng.; (United States)
- Additional Journal Information:
- Journal Volume: XXV:5
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; PLANT CELLS; METABOLISM; BIOCHEMICAL REACTION KINETICS; BIOMASS; BIOSYNTHESIS; ENERGY BALANCE; GROWTH; MASS BALANCE; REDOX REACTIONS; CHEMICAL REACTIONS; ENERGY SOURCES; KINETICS; REACTION KINETICS; RENEWABLE ENERGY SOURCES; SYNTHESIS; 550500* - Metabolism
Citation Formats
. Mass-energy balance for microbial product synthesis--biochemical and cultural aspects. United States: N. p., 1983.
Web.
. Mass-energy balance for microbial product synthesis--biochemical and cultural aspects. United States.
. 1983.
"Mass-energy balance for microbial product synthesis--biochemical and cultural aspects". United States.
@article{osti_5639696,
title = {Mass-energy balance for microbial product synthesis--biochemical and cultural aspects},
author = {},
abstractNote = {Interrelations between the rates of the product synthesis, cell biomass growth, respiration, and organic substrate consumption have been studied by the mass-energy balance method. This method is based on the utilization of a special unit of substance reducity, namely redoxon. Biochemical parameters have been found which are involved in these interrelations and which describe the processes of high-energy bond gain and energy expenditure during metabolism. In order to find these, the separation of the whole metabolism into several partial metabolisms has been applied. Equations have been obtained describing the dependences of the product yield and process specific productivity on the biochemical parameters and two macroscopic rates (e.g., rates of dilution and substrate consumption). Both aerobic and anaerobic product syntheses have been considered. The estimate of the upper limit of process productivity has been obtained. Mechanisms of the influence of the producer's intracellular characteristics on the rates of physiological processes and the culture productivity are discussed.},
doi = {},
url = {https://www.osti.gov/biblio/5639696},
journal = {Biotechnol. Bioeng.; (United States)},
number = ,
volume = XXV:5,
place = {United States},
year = {Sun May 01 00:00:00 EDT 1983},
month = {Sun May 01 00:00:00 EDT 1983}
}
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