Displacement effect in multicomponent chromatography
- Purdue Univ., West Lafayette, IN (US)
The study of interference effects is of fundamental importance in understanding multicomponent chromatography. In this paper a displacement effect is examined and shown to be able to explain the dominating interference effects in three major modes of chromatography - frontal, elution, and displacement - involving competitive isotherms. It is concluded that the concentration profile of a component usually becomes sharper due to the displacement effect from another component, while the concentration front of the displacer is usually diffused. Five factors that escalate the displacement effect in multicomponent elution were investigated. A binary elution with a competing modifier in the mobile phase was also discussed. This study was carried out using computer simulations based on a general nonlinear multicomponent rate equation model that considers axial dispersion, external mass transfer, intraparticle diffusion, and Langmuir isotherms. The use of the general model helps the visualization of the multicomponent interactions in chromatography under mass transfer conditions.
- Sponsoring Organization:
- National Science Foundation (NSF); National Science Foundation, Washington, DC (United States)
- OSTI ID:
- 5637461
- Journal Information:
- Industrial and Engineering Chemistry Research; (United States), Vol. 36:8; ISSN 0888-5885
- Country of Publication:
- United States
- Language:
- English
Similar Records
Experimental evidence of a delta-shock in nonlinear chromatography
Comparison of maximum production rates and optimum operating/design parameters in overloaded elution and displacement chromatography
Related Subjects
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
02 PETROLEUM
BINARY MIXTURES
FLOW VISUALIZATION
CHROMATOGRAPHY
PHASE STUDIES
DISPLACEMENT FLUIDS
CHEMICAL REACTION KINETICS
FLUIDS
EQUATIONS OF MOTION
FLUID FLOW
NONLINEAR PROBLEMS
COMPUTERIZED SIMULATION
DIFFUSION
DISPERSIONS
FLUID MECHANICS
ISOTHERMAL PROCESSES
MASS TRANSFER
PETROLEUM REFINERIES
TONKS-LANGMUIR THEORY
DIFFERENTIAL EQUATIONS
EQUATIONS
INDUSTRIAL PLANTS
KINETICS
MECHANICS
MIXTURES
PARTIAL DIFFERENTIAL EQUATIONS
REACTION KINETICS
SEPARATION PROCESSES
SIMULATION
400105* - Separation Procedures
020400 - Petroleum- Processing