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Title: Intrahepatic versus extrahepatic cholestasis. Discrimination with biliary scintigraphy combined with ultrasound

Abstract

Biliary scintigraphy and ultrasound imaging were performed in 52 patients with suspected biliary tract pathology. Results were correlated with the findings of direct cholangiography. Several new innovations in scintigraphic technique were used. The combination of ultrasound imaging and scintigraphy correctly identified biliary tract obstruction in 17 of 19 patients, 12 of whom had dilated bile ducts on ultrasonography. Intrahepatic cholestasis was correctly diagnosed in 11 of 13 patients. Accurate discrimination between intrahepatic and extrahepatic cholestasis was achieved in 28 of 32 patients (88%) with the combined studies. Scintigraphy also provided a correct diagnosis of acute cholecystitis in all 9 patients with surgically confirmed disease. Eleven additional patients with gallbladder or pancreatic disease had normal bile ducts at scintigraphy, which was confirmed with cholangiography. When combined with ultrasound imaging, modern biliary scintigraphy can (a) provide excellent discrimination between intrahepatic and extrahepatic cholestasis and (b) help determine the need for subsequent invasive diagnostic studies in selected patients.

Authors:
;
Publication Date:
Research Org.:
Portland Veterans Administration Medical Center, OR
OSTI Identifier:
5636404
Resource Type:
Journal Article
Journal Name:
Gastroenterology; (United States)
Additional Journal Information:
Journal Volume: 3
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BILIARY TRACT; PATHOLOGICAL CHANGES; SCINTISCANNING; DIGESTIVE SYSTEM DISEASES; DIAGNOSIS; PATIENTS; TECHNETIUM 99; ULTRASONOGRAPHY; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; COUNTING TECHNIQUES; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM; DISEASES; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; NUCLEI; ODD-EVEN NUCLEI; RADIOISOTOPE SCANNING; RADIOISOTOPES; TECHNETIUM ISOTOPES; YEARS LIVING RADIOISOTOPES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics

Citation Formats

Lieberman, D A, and Krishnamurthy, G T. Intrahepatic versus extrahepatic cholestasis. Discrimination with biliary scintigraphy combined with ultrasound. United States: N. p., 1986. Web.
Lieberman, D A, & Krishnamurthy, G T. Intrahepatic versus extrahepatic cholestasis. Discrimination with biliary scintigraphy combined with ultrasound. United States.
Lieberman, D A, and Krishnamurthy, G T. 1986. "Intrahepatic versus extrahepatic cholestasis. Discrimination with biliary scintigraphy combined with ultrasound". United States.
@article{osti_5636404,
title = {Intrahepatic versus extrahepatic cholestasis. Discrimination with biliary scintigraphy combined with ultrasound},
author = {Lieberman, D A and Krishnamurthy, G T},
abstractNote = {Biliary scintigraphy and ultrasound imaging were performed in 52 patients with suspected biliary tract pathology. Results were correlated with the findings of direct cholangiography. Several new innovations in scintigraphic technique were used. The combination of ultrasound imaging and scintigraphy correctly identified biliary tract obstruction in 17 of 19 patients, 12 of whom had dilated bile ducts on ultrasonography. Intrahepatic cholestasis was correctly diagnosed in 11 of 13 patients. Accurate discrimination between intrahepatic and extrahepatic cholestasis was achieved in 28 of 32 patients (88%) with the combined studies. Scintigraphy also provided a correct diagnosis of acute cholecystitis in all 9 patients with surgically confirmed disease. Eleven additional patients with gallbladder or pancreatic disease had normal bile ducts at scintigraphy, which was confirmed with cholangiography. When combined with ultrasound imaging, modern biliary scintigraphy can (a) provide excellent discrimination between intrahepatic and extrahepatic cholestasis and (b) help determine the need for subsequent invasive diagnostic studies in selected patients.},
doi = {},
url = {https://www.osti.gov/biblio/5636404}, journal = {Gastroenterology; (United States)},
number = ,
volume = 3,
place = {United States},
year = {Sat Mar 01 00:00:00 EST 1986},
month = {Sat Mar 01 00:00:00 EST 1986}
}