Cumulative effects from repeated exposures to ultraviolet radiation

Journal Article · Fri May 01 00:00:00 EDT 1981 · J. Invest. Dermatol.; (United States)

DOI:https://doi.org/10.1111/1523-1747.ep12520007· OSTI ID:5636401

Kaidbey, K H; Kligman, A M

Repeated exposures to subliminal doses of UVR, given at 24-hr intervals, resulted in a lowering of the erythema threshold dose. At erythemogenically equivalent doses, UV-A was the most effective and UV-C the least. A similar and more pronounced effect was observed following repeated exposures to subthreshold doses of UV-A and topically applied 8-methoxypsoralen. These findings provide quantitative evidence for the cumulative nature of acute UVR damage in human skin.

• OSTI ID: 5636401
• Journal Information: J. Invest. Dermatol.; (United States), Vol. 76:5
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ERYTHEMA
RADIOINDUCTION
PSORALEN
RADIOSENSITIVITY EFFECTS
SKIN
BIOLOGICAL RADIATION EFFECTS
DOSE-RESPONSE RELATIONSHIPS
FRACTIONATED IRRADIATION
RADIATION DOSES
THRESHOLD DOSE
ULTRAVIOLET RADIATION
ANTICOAGULANTS
BIOLOGICAL EFFECTS
BODY
COUMARINS
DOSES
DRUGS
ELECTROMAGNETIC RADIATION
HEMATOLOGIC AGENTS
HETEROCYCLIC COMPOUNDS
IRRADIATION
ORGANIC COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
ORGANS
RADIATION EFFECTS
RADIATIONS
SYMPTOMS
560151* - Radiation Effects on Animals- Man