Radiation-induced cystitis following intracavitary irradiation for superficial bladder cancer
Intracavitary irradiation is effective in the treatment of noninvasive papillary transitional cell carcinoma and carcinoma in situ of the bladder. Mortality has not been associated with this form of therapy. The morbidity associated with intracavitary irradiation consists of mild to severe radiation cystitis and we report 2 such cases. One patient is from a series of 65 patients with noninvasive bladder tumors treated with intracavitary irradiation at this clinic since 1965. The second patient had noninvasive bladder tumors and was treated with intracavitary irradiation elsewhere. In both patients severe radiation cystitis subsequently developed, requiring simple cystectomy and urinary diversion. The potential for this serious side effect must be considered when choosing a form of therapy for patients with noninvasive papillary transitional cell carcinoma and carcinoma in situ of the bladder.
- Research Organization:
- Department of Urology, Cleveland Clinic Foundation, Ohio
- OSTI ID:
- 5605426
- Journal Information:
- J. Urol.; (United States), Vol. 130:2
- Country of Publication:
- United States
- Language:
- English
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63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BLADDER
BIOLOGICAL RADIATION EFFECTS
CARCINOMAS
RADIOTHERAPY
SIDE EFFECTS
INFLAMMATION
SURGERY
BIOLOGICAL EFFECTS
BODY
DISEASES
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
PATHOLOGICAL CHANGES
RADIATION EFFECTS
RADIOLOGY
SYMPTOMS
THERAPY
URINARY TRACT
550604* - Medicine- Unsealed Radionuclides in Therapy- (1980-)
560151 - Radiation Effects on Animals- Man