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Title: Radiation-induced injury of the esophagus

Abstract

Forty patients with functional or morphologic esophageal abnormalities following radiotherapy were identified. Abnormalities included abnormal motility with and without mucosal edema, stricture, ulceration and pseudodiverticulum, and fistula. Abnormal motility occurred 4 to 12 weeks following radiotherapy alone and as early as 1 week after therapy when concomitant chemotherapy had been given. Strictures developed 4 to 8 months following completion of radiotherapy. Ulceration, pseudodiverticulum, and fistula formation did not develop in a uniform time frame. Radiation-induced esophageal injury is more frequent when radiotherapy and chemotherapy are combined than it is with radiotherapy alone.

Authors:
;
Publication Date:
Research Org.:
Department of Diagnostic Radiology, University of Texas, M. D. Anderson Hospital and Tumor Institute, Houston
OSTI Identifier:
5514695
Resource Type:
Journal Article
Resource Relation:
Journal Name: Radiology; (United States); Journal Volume: 148:2
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; ESOPHAGUS; RADIATION INJURIES; RADIOTHERAPY; SIDE EFFECTS; CHEMOTHERAPY; SYNERGISM; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BODY; DIGESTIVE SYSTEM; INJURIES; MEDICINE; NUCLEAR MEDICINE; ORGANS; RADIATION EFFECTS; RADIOLOGY; THERAPY; 560151* - Radiation Effects on Animals- Man

Citation Formats

Lepke, R.A., and Libshitz, H.I.. Radiation-induced injury of the esophagus. United States: N. p., 1983. Web. doi:10.1148/radiology.148.2.6867327.
Lepke, R.A., & Libshitz, H.I.. Radiation-induced injury of the esophagus. United States. doi:10.1148/radiology.148.2.6867327.
Lepke, R.A., and Libshitz, H.I.. Mon . "Radiation-induced injury of the esophagus". United States. doi:10.1148/radiology.148.2.6867327.
@article{osti_5514695,
title = {Radiation-induced injury of the esophagus},
author = {Lepke, R.A. and Libshitz, H.I.},
abstractNote = {Forty patients with functional or morphologic esophageal abnormalities following radiotherapy were identified. Abnormalities included abnormal motility with and without mucosal edema, stricture, ulceration and pseudodiverticulum, and fistula. Abnormal motility occurred 4 to 12 weeks following radiotherapy alone and as early as 1 week after therapy when concomitant chemotherapy had been given. Strictures developed 4 to 8 months following completion of radiotherapy. Ulceration, pseudodiverticulum, and fistula formation did not develop in a uniform time frame. Radiation-induced esophageal injury is more frequent when radiotherapy and chemotherapy are combined than it is with radiotherapy alone.},
doi = {10.1148/radiology.148.2.6867327},
journal = {Radiology; (United States)},
number = ,
volume = 148:2,
place = {United States},
year = {Mon Aug 01 00:00:00 EDT 1983},
month = {Mon Aug 01 00:00:00 EDT 1983}
}