Absorption and scattering of laser light in biological media - Mathematical modeling and methods for determining the optical properties
First, a mathematical model for light scattering in homogeneous media is developed. Second, methods for determining the optical properties of tissue such as absorption and scattering coefficients and the phase function are introduced. The proposed seven flux model approximates light scattering using seven directional fluxes. An analytic solution for a one dimensional geometry and numerical solutions for higher dimensional geometries are presented. The behavior of the seven flux model is examined by correlating it with more accurate solutions of radiative transfer theory. The proposed model provides improved results compared with the currently-used models such as Kubelka-Munk theory and the diffusion approximation, and as well as allowing geometrical flexibilities which are difficult to achieve with more accurate solutions. Next, new methods are developed to determine optical properties. Absorption and scattering coefficients are determined base don transmission measurements for isotropic scattering. Additional measurements of the phase function and collimated attenuation are required for anisotropic scattering. Measurements with the gel samples and the human aortic walls at the wavelength of 633 nm show highly forward scattering behaviors.
- Research Organization:
- Texas Univ., Austin, TX (USA)
- OSTI ID:
- 5511933
- Resource Relation:
- Other Information: Thesis (Ph. D.)
- Country of Publication:
- United States
- Language:
- English
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LASER RADIATION
BIOLOGICAL EFFECTS
OPTICAL PROPERTIES
MEASURING METHODS
ABSORPTION
AORTA
MAN
MATHEMATICAL MODELS
ANIMALS
ARTERIES
BLOOD VESSELS
BODY
CARDIOVASCULAR SYSTEM
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MAMMALS
ORGANS
PHYSICAL PROPERTIES
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