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Title: Determination of iodide in metabolic studies of 125I-labeled compounds

Abstract

Methods capable of measuring inorganic iodide in the presence of other highly polar metabolites were developed in support of studies concerning the metabolism of 125I-labeled compounds. The methods included separation of iodine on a weekly basic resin paper followed by gamma-counting, methyl iodide exchange, and reverse isotopic dilution.

Authors:
;
Publication Date:
Research Org.:
Univ. of Michigan, Ann Arbor
OSTI Identifier:
5509985
Resource Type:
Journal Article
Journal Name:
J. Pharm. Sci.; (United States)
Additional Journal Information:
Journal Volume: 68:2
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; 62 RADIOLOGY AND NUCLEAR MEDICINE; 63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; IODIDES; QUANTITATIVE CHEMICAL ANALYSIS; URINE; RADIOCHEMICAL ANALYSIS; CHROMATOGRAPHY; IODINE 125; ISOTOPE DILUTION; LABELLED COMPOUNDS; METABOLISM; RATS; ANIMALS; BETA DECAY RADIOISOTOPES; BIOLOGICAL MATERIALS; BIOLOGICAL WASTES; BODY FLUIDS; CHEMICAL ANALYSIS; DAYS LIVING RADIOISOTOPES; ELECTRON CAPTURE RADIOISOTOPES; HALIDES; HALOGEN COMPOUNDS; INTERMEDIATE MASS NUCLEI; IODINE COMPOUNDS; IODINE ISOTOPES; ISOTOPE APPLICATIONS; ISOTOPES; MAMMALS; MATERIALS; NUCLEI; ODD-EVEN NUCLEI; RADIOISOTOPES; RODENTS; SEPARATION PROCESSES; TRACER TECHNIQUES; VERTEBRATES; WASTES; 400103* - Radiometric & Radiochemical Procedures- (-1987); 550601 - Medicine- Unsealed Radionuclides in Diagnostics; 560172 - Radiation Effects- Nuclide Kinetics & Toxicology- Animals- (-1987)

Citation Formats

Shum, Y.Y., and Sinsheimer, J.E. Determination of iodide in metabolic studies of 125I-labeled compounds. United States: N. p., 1979. Web. doi:10.1002/jps.2600680241.
Shum, Y.Y., & Sinsheimer, J.E. Determination of iodide in metabolic studies of 125I-labeled compounds. United States. doi:10.1002/jps.2600680241.
Shum, Y.Y., and Sinsheimer, J.E. Thu . "Determination of iodide in metabolic studies of 125I-labeled compounds". United States. doi:10.1002/jps.2600680241.
@article{osti_5509985,
title = {Determination of iodide in metabolic studies of 125I-labeled compounds},
author = {Shum, Y.Y. and Sinsheimer, J.E.},
abstractNote = {Methods capable of measuring inorganic iodide in the presence of other highly polar metabolites were developed in support of studies concerning the metabolism of 125I-labeled compounds. The methods included separation of iodine on a weekly basic resin paper followed by gamma-counting, methyl iodide exchange, and reverse isotopic dilution.},
doi = {10.1002/jps.2600680241},
journal = {J. Pharm. Sci.; (United States)},
number = ,
volume = 68:2,
place = {United States},
year = {1979},
month = {2}
}