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Title: Studies in time-of-flight mass spectrometry: improved mass resolving power and versatility, and mass spectrometry/mass spectrometry by time-resolved ion kinetic energy spectrometery

Abstract

A new time-of-flight (TOF) mass spectrometer, the Beam Deflection Energy-Resolved TOF mass spectrometer (BEDER-TOF) has been designed and constructed. The instrument combines the advantages of beam deflection for ion pulse formation with an electrostatic analyzer which reduces the energy spread of the ions admitted to the TOF region. The instrument is able to use ion sources which cannot be pulsed on a time scale suitable for conventional TOF analysis (e.g., chemical ionization sources). Improved mass resolution is demonstrated over a wide mass range in such a manner that all the ions are in focus simultaneously. A full-width-at-half-maximum resolution of 982 is achieved for the molecular ion peak of perfluorotributylamine at m/z 614. A preliminary investigation of a proposed technique for collecting information typically obtained by tandem mass spectrometry (MS/MS) has been conducted using the BEDER-TOF. This new method, named time-resolved ion kinetic energy spectrometery (TRIKES), combines time-of-flight (velocity) and kinetic energy analysis of undissociated parent ions and the ionic products of parent ion dissociations, (daughter ions) which occur between the ion electrostatic analyzer of the BEDER-TOF. Unit resolution of the daughter ions produced upon metastable decomposition of the molecular ion of n-decane has been achieved in daughter scans. The realizationmore » of rapid time-of-flight data collection rates in TRIKES may yield improved data collection rates in MS/MS.« less

Authors:
Publication Date:
Research Org.:
Michigan State Univ., East Lansing (USA)
OSTI Identifier:
5502719
Alternate Identifier(s):
OSTI ID: 5502719
Resource Type:
Thesis/Dissertation
Resource Relation:
Other Information: Thesis (Ph. D.)
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; TIME-OF-FLIGHT SPECTROMETERS; DESIGN; MEASURING INSTRUMENTS; SPECTROMETERS 400104* -- Spectral Procedures-- (-1987)

Citation Formats

Pinkston, J.D. Studies in time-of-flight mass spectrometry: improved mass resolving power and versatility, and mass spectrometry/mass spectrometry by time-resolved ion kinetic energy spectrometery. United States: N. p., 1985. Web.
Pinkston, J.D. Studies in time-of-flight mass spectrometry: improved mass resolving power and versatility, and mass spectrometry/mass spectrometry by time-resolved ion kinetic energy spectrometery. United States.
Pinkston, J.D. Tue . "Studies in time-of-flight mass spectrometry: improved mass resolving power and versatility, and mass spectrometry/mass spectrometry by time-resolved ion kinetic energy spectrometery". United States.
@article{osti_5502719,
title = {Studies in time-of-flight mass spectrometry: improved mass resolving power and versatility, and mass spectrometry/mass spectrometry by time-resolved ion kinetic energy spectrometery},
author = {Pinkston, J.D.},
abstractNote = {A new time-of-flight (TOF) mass spectrometer, the Beam Deflection Energy-Resolved TOF mass spectrometer (BEDER-TOF) has been designed and constructed. The instrument combines the advantages of beam deflection for ion pulse formation with an electrostatic analyzer which reduces the energy spread of the ions admitted to the TOF region. The instrument is able to use ion sources which cannot be pulsed on a time scale suitable for conventional TOF analysis (e.g., chemical ionization sources). Improved mass resolution is demonstrated over a wide mass range in such a manner that all the ions are in focus simultaneously. A full-width-at-half-maximum resolution of 982 is achieved for the molecular ion peak of perfluorotributylamine at m/z 614. A preliminary investigation of a proposed technique for collecting information typically obtained by tandem mass spectrometry (MS/MS) has been conducted using the BEDER-TOF. This new method, named time-resolved ion kinetic energy spectrometery (TRIKES), combines time-of-flight (velocity) and kinetic energy analysis of undissociated parent ions and the ionic products of parent ion dissociations, (daughter ions) which occur between the ion electrostatic analyzer of the BEDER-TOF. Unit resolution of the daughter ions produced upon metastable decomposition of the molecular ion of n-decane has been achieved in daughter scans. The realization of rapid time-of-flight data collection rates in TRIKES may yield improved data collection rates in MS/MS.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1985},
month = {1}
}

Thesis/Dissertation:
Other availability
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