Induction of benzo(a)pyrene monooxygenase in fish and the Salmonella test as a tool for detecting mutagenic/carcinogenic xenobiotics in the aquatic environment

Journal Article · Sun Apr 01 00:00:00 EST 1979 · Bull. Environ. Contam. Toxicol.; (United States)

DOI:https://doi.org/10.1007/BF01685508· OSTI ID:5500010

Kurelec, B ^[1]; Matijasevic, Z; Rijavec, M; Alacevic, M; Britvic, S; Mueller, W E.G.; Zahn, R K

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1. Rudjer Boskovic Inst., Zagreb, Yugoslavia

From the ecological point of view and on account of the interest in the environmental assessment of biological effects of xenobiotics on water organisms, it would be highly desirable to detect their presence by an equally revealing biochemical method in water samples. Considering the induction of BPMO as a means of detoxification in fish, we studied the consequences of i/p application of polluted water extracts from different marine sites to young carp. Aliquots of these extracts served in Salmonella/microsome mutagenicity tests using liver homogenates of pollution-induced fish as activating systems. The results we obtained so far are presented in this paper.

• OSTI ID: 5500010
• Journal Information: Bull. Environ. Contam. Toxicol.; (United States), Vol. 21:6
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
54 ENVIRONMENTAL SCIENCES
02 PETROLEUM
FISHES
BIOCHEMICAL REACTION KINETICS
PETROLEUM
WATER POLLUTION
SALMONELLA
MUTAGEN SCREENING
AQUATIC ECOSYSTEMS
BIOASSAY
BIOLOGICAL PATHWAYS
CARCINOGENESIS
MUTAGENESIS
OXIDOREDUCTASES
WATER POLLUTION MONITORS
ANIMALS
AQUATIC ORGANISMS
BACTERIA
ECOSYSTEMS
ENERGY SOURCES
ENZYMES
FOSSIL FUELS
FUELS
KINETICS
MICROORGANISMS
PATHOGENESIS
POLLUTION
REACTION KINETICS
SCREENING
VERTEBRATES
560305* - Chemicals Metabolism & Toxicology- Vertebrates- (-1987)
560304 - Chemicals Metabolism & Toxicology- Invertebrates- (-1987)
520200 - Environment
Aquatic- Chemicals Monitoring & Transport- (-1989)
020900 - Petroleum- Environmental Aspects