Targetry for the production of medical isotopes
A high-pressure, low volume, cryogenically-cooled gas target has been developed for tandem Van de Graaff production of medical radiotracers. High yields and radionuclidically pure products are made possible by the use of enriched target materials. The inert Kr-81m (t 1/2 - 13 sec) from the /sup 80/Kr(d,n)/sup 81/Rb reaction permits continuous administration from a generator for regional pulmonary ventilation studies. Cryo-pumping and reclamation procedures enhance the economic feasibility of using enriched isotopes by minimizing target losses. Direct extrapolation of those techniques to cyclotron targetry is possible. A low-volume, enriched solid target employing the /sup 50/Cr(d,n)/sup 51/Mn reaction has been developed. The mitochondrial concentration of Mn in the heart muscle enables Mn-51 to be used as a myocardial imaging agent.
- Research Organization:
- University of Wisconsin, Madison, Wisconsin 53706
- OSTI ID:
- 5477899
- Report Number(s):
- CONF-801111-
- Journal Information:
- IEEE Trans. Nucl. Sci.; (United States), Vol. NS-28:2; Conference: 6. conference on application of accelerators in research and industry, Denton, TX, USA, 3 Nov 1980
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
43 PARTICLE ACCELERATORS
38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY
RADIOISOTOPES
NUCLEAR MEDICINE
PRODUCTION
VAN DE GRAAFF ACCELERATORS
CHROMIUM 50
CYCLOTRONS
DESIGN
IRRADIATION
KRYPTON 80
LUNGS
MANGANESE 51
MYOCARDIUM
RUBIDIUM 81
TARGETS
ACCELERATORS
ALKALI METAL ISOTOPES
BETA DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BODY
CARDIOVASCULAR SYSTEM
CHROMIUM ISOTOPES
CYCLIC ACCELERATORS
ELECTRON CAPTURE RADIOISOTOPES
ELECTROSTATIC ACCELERATORS
EVEN-EVEN NUCLEI
HEART
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
KRYPTON ISOTOPES
MANGANESE ISOTOPES
MEDICINE
MINUTES LIVING RADIOISOTOPES
MUSCLES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RESPIRATORY SYSTEM
RUBIDIUM ISOTOPES
STABLE ISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics
430303 - Particle Accelerators- Experimental Facilities & Equipment
400703 - Radiochemistry & Nuclear Chemistry- Radioisotope Production