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Title: Investigation of selected potential environmental contaminants: ethylene glycol, propylene glycols and butylene glycols. Final report

Abstract

This report reviews aspects of production, use, environmental exposure and biological effects of ethylene glycol, two isomers of propylene glycol (1,2- and 1,3-propanediol) and four isomers of butylene glycol (1,3-, 1,4-, 2,3-, and 1,2- butanediol). Annual production of ethylene glycol is about 3.7 billion pounds for use primarily in antifreeze and polyester fiber. About 0.5 billion pounds of 1,2-propanediol are produced per year for use in polyester resins, food, pharmaceuticals, and cellophane. Annual domestic demand for 1,4-butanediol is about 0.2 billion pounds for use in the production of tetra-hydrofuran and acetylenic chemicals. The other title glycols are of less importance commercially. The major source of environmental contamination by ethylene glycol and 1,2-propanediol is likely from the disposal of spent antifreeze and de-icing fluids. However, limited monitoring data make it difficult to adequately assess environmental exposure to the glycols. The glycols are capable of being degraded by a variety of acclimated and unacclimated soil, water, and sewage microorganisms. In humans, ethylene glycol intoxication, usually as a result of accidental ingestion of antifreeze, may result in nausea, hypertension, tachycardia, cardiopulmonary failure, renal impairment, coma and death. 1,2-Propanediol is a GRAS food additive of low toxicity. 1,3-Butanediol has been studied as a sourcemore » of dietary energy. Few studies are available on 1,2-, 2,3- and 1,4-butanediol or on 1,3-propanediol.« less

Authors:
Publication Date:
Research Org.:
Franklin Research Center, Philadelphia, PA (USA). Science Information Services Organization
OSTI Identifier:
5462228
Alternate Identifier(s):
OSTI ID: 5462228
Report Number(s):
PB-80-109119
DOE Contract Number:  
EPA-68-01-3893
Resource Type:
Technical Report
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; GLYCOLS; BIOLOGICAL EFFECTS; ADDITIVES; AIR POLLUTION; ANIMALS; ANTIFREEZE; CHEMICAL INDUSTRY; CHEMICAL PROPERTIES; ENVIRONMENTAL IMPACTS; INDUSTRIAL WASTES; ISOMERS; MAN; MANUFACTURING; MARKETING; METABOLISM; ORGANIC COMPOUNDS; PHYSICAL PROPERTIES; PUBLIC HEALTH; REGULATIONS; STANDARDS; TOXICITY; WATER POLLUTION; ALCOHOLS; HYDROXY COMPOUNDS; INDUSTRY; MAMMALS; POLLUTION; PRIMATES; VERTEBRATES; WASTES 560306* -- Chemicals Metabolism & Toxicology-- Man-- (-1987)

Citation Formats

Miller, L.M. Investigation of selected potential environmental contaminants: ethylene glycol, propylene glycols and butylene glycols. Final report. United States: N. p., 1979. Web.
Miller, L.M. Investigation of selected potential environmental contaminants: ethylene glycol, propylene glycols and butylene glycols. Final report. United States.
Miller, L.M. Tue . "Investigation of selected potential environmental contaminants: ethylene glycol, propylene glycols and butylene glycols. Final report". United States.
@article{osti_5462228,
title = {Investigation of selected potential environmental contaminants: ethylene glycol, propylene glycols and butylene glycols. Final report},
author = {Miller, L.M.},
abstractNote = {This report reviews aspects of production, use, environmental exposure and biological effects of ethylene glycol, two isomers of propylene glycol (1,2- and 1,3-propanediol) and four isomers of butylene glycol (1,3-, 1,4-, 2,3-, and 1,2- butanediol). Annual production of ethylene glycol is about 3.7 billion pounds for use primarily in antifreeze and polyester fiber. About 0.5 billion pounds of 1,2-propanediol are produced per year for use in polyester resins, food, pharmaceuticals, and cellophane. Annual domestic demand for 1,4-butanediol is about 0.2 billion pounds for use in the production of tetra-hydrofuran and acetylenic chemicals. The other title glycols are of less importance commercially. The major source of environmental contamination by ethylene glycol and 1,2-propanediol is likely from the disposal of spent antifreeze and de-icing fluids. However, limited monitoring data make it difficult to adequately assess environmental exposure to the glycols. The glycols are capable of being degraded by a variety of acclimated and unacclimated soil, water, and sewage microorganisms. In humans, ethylene glycol intoxication, usually as a result of accidental ingestion of antifreeze, may result in nausea, hypertension, tachycardia, cardiopulmonary failure, renal impairment, coma and death. 1,2-Propanediol is a GRAS food additive of low toxicity. 1,3-Butanediol has been studied as a source of dietary energy. Few studies are available on 1,2-, 2,3- and 1,4-butanediol or on 1,3-propanediol.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1979},
month = {5}
}

Technical Report:
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