Epidemiological follow-up study of Japanese Thorotrast cases
- Kanagawa Prefectural Coll. of Nursing and Medical Tech., Nakao, Japan
The authors conducted a follow-up study on 243 Thorotrast-administered war-wounded ex-servicemen in 1975, after a lapse of 30 to 38 years from Thorotrast injections, and found 18 cases of malignant hepatic tumor, 15 cases of other malignant tumors, 2 cases of blood diseases, and 9 cases of liver cirrhosis in 224 cases who had been given Thorotrast intravascularly. The incidence of hepatic and other malignant tumors, blood diseases, and liver cirrhosis was significantly higher than in the controls. The total number of deaths in the Thorotrast-administered cases was also significantly higher than in the controls. In the remaining 19 cases who had been given Thorotrast by a route other than intravascularly, no fatal case related to Thorotrast administration was discovered. In the living cases, however, one sarcoma was observed to have developed at the site of the Thorotrast injection.
- OSTI ID:
- 5457200
- Journal Information:
- Environ. Res.; (United States), Vol. 18:1
- Country of Publication:
- United States
- Language:
- English
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62 RADIOLOGY AND NUCLEAR MEDICINE
BLOOD PLASMA
DELAYED RADIATION EFFECTS
HEMIC DISEASES
RADIOINDUCTION
LIVER
LIVER CIRRHOSIS
NEOPLASMS
THOROTRAST
SIDE EFFECTS
JAPAN
MEDICAL SURVEILLANCE
PATIENTS
RADIONUCLIDE ADMINISTRATION
ACTINIDE COMPOUNDS
ASIA
BIOLOGICAL EFFECTS
BIOLOGICAL MATERIALS
BIOLOGICAL RADIATION EFFECTS
BLOOD
BODY
BODY FLUIDS
CHALCOGENIDES
COLLOIDS
CONTRAST MEDIA
DIGESTIVE SYSTEM
DIGESTIVE SYSTEM DISEASES
DISEASES
DISPERSIONS
GLANDS
MATERIALS
ORGANS
OXIDES
OXYGEN COMPOUNDS
RADIATION EFFECTS
RADIOCOLLOIDS
THORIUM COMPOUNDS
THORIUM OXIDES
560171* - Radiation Effects- Nuclide Kinetics & Toxicology- Man- (-1987)
550601 - Medicine- Unsealed Radionuclides in Diagnostics