Whole abdomen radiation for minimal residual epithelial ovarian carcinoma after surgical resection and maximal first-line chemotherapy

Journal Article · Mon Feb 01 00:00:00 EST 1988 · Gynecol. Oncol.; (United States)

DOI:https://doi.org/10.1016/0090-8258(88)90211-9· OSTI ID:5433416

Cain, J M; Russell, A H; Greer, B E; Tamimi, H K; Figge, D C

Ten patients with Stage III epithelial ovarian received whole abdomen radiation therapy after extensive courses of chemotherapy and second or third laparotomies. All patients had less than 2-mm diameter residual disease. The major side effect was bone marrow suppression which led to decreased dose or field size in four patients. Five patients have recurred and three of these have died. Further treatment after recurrence was compromised by bone marrow suppression. While 40-50% of selected patients may respond to this approach, numerous alternatives are being explored that would not handicap further treatment to the same degree and may have equal response rates.

• Research Organization: Univ. of Washington, Seattle (USA)
• OSTI ID: 5433416
• Journal Information: Gynecol. Oncol.; (United States), Vol. 29:2
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
CARCINOMAS
COMBINED THERAPY
SURGERY
OVARIES
ABDOMEN
PATIENTS
BODY
BODY AREAS
DISEASES
FEMALE GENITALS
GONADS
MEDICINE
NEOPLASMS
ORGANS
THERAPY
550603* - Medicine- External Radiation in Therapy- (1980-)
550600 - Medicine