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Title: Noninvasive ergonovine maleate provocative testing for coronary artery spasm: the need for routine thallium-201 imaging

Abstract

We administered ergonovine and used both electrocardiographic monitoring and thallium-/sup 201/ (/sup 201/Tl) imaging to detect reversible ischemia in 100 patients. Patients already established as having coronary artery spasm and those with nonbypassed, proximal, high-grade coronary artery stenosis were excluded. No complication occurred in any patient. The use of thallium imaging in addition to electrocardiographic monitoring resulted in a higher degree of sensitivity than did ECG monitoring alone. Fourteen patients demonstrated evidence of coronary artery spasm as documented by /sup 201/Tl imaging but of the 14, significant ECG changes occurred in only 50%, and classic ST segment elevation in 21%. Thus, in carefully selected patients the noninvasive provocation of coronary spasm can be accomplished safely, but ECG monitoring must be combined with thallium-/sup 201/ imaging to achieve an acceptable degree of sensitivity.

Authors:
; ; ; ; ;
Publication Date:
Research Org.:
Jewish Hospital of St. Louis, Washington University, MO
OSTI Identifier:
5428555
Resource Type:
Journal Article
Journal Name:
Cathet. Cardiovasc. Diagn.; (United States)
Additional Journal Information:
Journal Volume: 9:3
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; CORONARIES; CONTRACTION; RADIOISOTOPE SCANNING; THALLIUM 201; DIAGNOSTIC USES; ELECTROCARDIOGRAMS; ISCHEMIA; PATIENTS; VASCULAR DISEASES; VASOCONSTRICTION; ARTERIES; BETA DECAY RADIOISOTOPES; BLOOD VESSELS; BODY; CARDIOVASCULAR DISEASES; CARDIOVASCULAR SYSTEM; COUNTING TECHNIQUES; DAYS LIVING RADIOISOTOPES; DIAGRAMS; DISEASES; ELECTRON CAPTURE RADIOISOTOPES; HEAVY NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; NUCLEI; ODD-EVEN NUCLEI; ORGANS; RADIOISOTOPES; SECONDS LIVING RADIOISOTOPES; THALLIUM ISOTOPES; USES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics

Citation Formats

Shanes, J.G., Krone, R.J., Fisher, K., Shah, B., Eisenkramer, G., and Humphrey, J.R. Noninvasive ergonovine maleate provocative testing for coronary artery spasm: the need for routine thallium-201 imaging. United States: N. p., 1983. Web. doi:10.1002/ccd.1810090306.
Shanes, J.G., Krone, R.J., Fisher, K., Shah, B., Eisenkramer, G., & Humphrey, J.R. Noninvasive ergonovine maleate provocative testing for coronary artery spasm: the need for routine thallium-201 imaging. United States. doi:10.1002/ccd.1810090306.
Shanes, J.G., Krone, R.J., Fisher, K., Shah, B., Eisenkramer, G., and Humphrey, J.R. Sat . "Noninvasive ergonovine maleate provocative testing for coronary artery spasm: the need for routine thallium-201 imaging". United States. doi:10.1002/ccd.1810090306.
@article{osti_5428555,
title = {Noninvasive ergonovine maleate provocative testing for coronary artery spasm: the need for routine thallium-201 imaging},
author = {Shanes, J.G. and Krone, R.J. and Fisher, K. and Shah, B. and Eisenkramer, G. and Humphrey, J.R.},
abstractNote = {We administered ergonovine and used both electrocardiographic monitoring and thallium-/sup 201/ (/sup 201/Tl) imaging to detect reversible ischemia in 100 patients. Patients already established as having coronary artery spasm and those with nonbypassed, proximal, high-grade coronary artery stenosis were excluded. No complication occurred in any patient. The use of thallium imaging in addition to electrocardiographic monitoring resulted in a higher degree of sensitivity than did ECG monitoring alone. Fourteen patients demonstrated evidence of coronary artery spasm as documented by /sup 201/Tl imaging but of the 14, significant ECG changes occurred in only 50%, and classic ST segment elevation in 21%. Thus, in carefully selected patients the noninvasive provocation of coronary spasm can be accomplished safely, but ECG monitoring must be combined with thallium-/sup 201/ imaging to achieve an acceptable degree of sensitivity.},
doi = {10.1002/ccd.1810090306},
journal = {Cathet. Cardiovasc. Diagn.; (United States)},
number = ,
volume = 9:3,
place = {United States},
year = {1983},
month = {1}
}