Novel photoaffinity label for the dopamine D2 receptor: synthesis of 4-azido-5-iodo-2-methoxy-N-1-(phenylmethyl)-4-piperidinyl benzamide (iodoazidoclebopride, IAC) and the corresponding /sup 125/I-labeled analogue (/sup 125/IAC)
Journal Article
·
· J. Med. Chem.; (United States)
- Research Organization:
- Northeastern Univ., Boston, MA
- OSTI ID:
- 5411257
- Journal Information:
- J. Med. Chem.; (United States), Vol. 28:4
- Country of Publication:
- United States
- Language:
- English
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N-(3-(p-azido-m-(/sup 125/I)iodophenyl)propionyl)-succinimide--a heterobifunctional reagent for the synthesis of radioactive photoaffinity ligands: synthesis of a carrier-free /sup 125/I-labeled cardiac glycoside photoaffinity label
Synthesis and characterization of new adenosine A/sub 1/ receptor radioligands, N/sup 6/-3-/sup 125/IODO-4-aminobenzyladenosine, and a photoaffinity probe, N/sup 6/-3-/sup 125/IODO-4-azidobenzyladenosine
Journal Article
·
Sun May 01 00:00:00 EDT 1988
· J. Med. Chem.; (United States)
·
OSTI ID:5411257
+3 more
N-(3-(p-azido-m-(/sup 125/I)iodophenyl)propionyl)-succinimide--a heterobifunctional reagent for the synthesis of radioactive photoaffinity ligands: synthesis of a carrier-free /sup 125/I-labeled cardiac glycoside photoaffinity label
Journal Article
·
Fri Jan 01 00:00:00 EST 1988
· Anal. Biochem.; (United States)
·
OSTI ID:5411257
Synthesis and characterization of new adenosine A/sub 1/ receptor radioligands, N/sup 6/-3-/sup 125/IODO-4-aminobenzyladenosine, and a photoaffinity probe, N/sup 6/-3-/sup 125/IODO-4-azidobenzyladenosine
Thesis/Dissertation
·
Wed Jan 01 00:00:00 EST 1986
·
OSTI ID:5411257
Related Subjects
59 BASIC BIOLOGICAL SCIENCES
AZIDO COMPOUNDS
BIOSYNTHESIS
RECEPTORS
LABELLING
AFFINITY
DOPAMINE
IODINE 125
IODINE COMPOUNDS
PHOTOLYSIS
RATS
TRACER TECHNIQUES
AMINES
ANIMALS
AROMATICS
AUTONOMIC NERVOUS SYSTEM AGENTS
BETA DECAY RADIOISOTOPES
CARDIOTONICS
CARDIOVASCULAR AGENTS
CHEMICAL REACTIONS
DAYS LIVING RADIOISOTOPES
DECOMPOSITION
DRUGS
ELECTRON CAPTURE RADIOISOTOPES
HALOGEN COMPOUNDS
HYDROXY COMPOUNDS
INTERMEDIATE MASS NUCLEI
IODINE ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
MAMMALS
NEUROREGULATORS
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PHENOLS
PHOTOCHEMICAL REACTIONS
POLYPHENOLS
RADIOISOTOPES
RODENTS
SYMPATHOMIMETICS
SYNTHESIS
VERTEBRATES
550201* - Biochemistry- Tracer Techniques
AZIDO COMPOUNDS
BIOSYNTHESIS
RECEPTORS
LABELLING
AFFINITY
DOPAMINE
IODINE 125
IODINE COMPOUNDS
PHOTOLYSIS
RATS
TRACER TECHNIQUES
AMINES
ANIMALS
AROMATICS
AUTONOMIC NERVOUS SYSTEM AGENTS
BETA DECAY RADIOISOTOPES
CARDIOTONICS
CARDIOVASCULAR AGENTS
CHEMICAL REACTIONS
DAYS LIVING RADIOISOTOPES
DECOMPOSITION
DRUGS
ELECTRON CAPTURE RADIOISOTOPES
HALOGEN COMPOUNDS
HYDROXY COMPOUNDS
INTERMEDIATE MASS NUCLEI
IODINE ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
MAMMALS
NEUROREGULATORS
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PHENOLS
PHOTOCHEMICAL REACTIONS
POLYPHENOLS
RADIOISOTOPES
RODENTS
SYMPATHOMIMETICS
SYNTHESIS
VERTEBRATES
550201* - Biochemistry- Tracer Techniques