Thyroid uptake and imaging with iodine-123 at 4-5 hours: replacement of the 24-hour iodine-131 standard
A study was carried out to determine the suitability of utilizing a 4 to 5 hr interval from administration of Iodine-123 to imaging and uptake measurement as a replacement for the 24-hr standard originally established with Iodine-131. In 55 patients who underwent scintigraphy at 4 and 24 hr, there was no discrepancy between paired images. In 55 patients who had uptake measured at 4 and 24 hr and in 191 patients who had uptake measured at 5 and 24 hr, the early measurements proved equal or better discriminants of euthyroid from hyperthyroid patients. In our institutions, these findings and the logistical advantages of completing the exam in 4-5 hr led us to abandon the 24-hr study in the majority of patients.
- Research Organization:
- David Grant USAF Medical Center, Travis AFB, CA
- OSTI ID:
- 5400755
- Journal Information:
- J. Nucl. Med.; (United States), Vol. 26:8
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
ENDOCRINE DISEASES
DIAGNOSIS
IODINE 123
UPTAKE
THYROID
SCINTISCANNING
CALIBRATION STANDARDS
HYPOTHYROIDISM
IODINE 131
PATIENTS
THYROIDITIS
TIME DEPENDENCE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
ENDOCRINE GLANDS
GLANDS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
IODINE ISOTOPES
ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPE SCANNING
RADIOISOTOPES
STANDARDS
550601* - Medicine- Unsealed Radionuclides in Diagnostics