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Title: Guided percutaneous fine-needle aspiration biopsy of the liver

Abstract

Forty patients with suspected malignant disease of the liver underwent percutaneous fine-needle aspiration biopsy with radioisotope scintigraphic and fluoroscopic guidance. The needle was aimed at focal defects identified on the liver scan and several passes were made. When the scan was diffusely abnormal, the liver was widely sampled with multiple passes. Thirty patients were eventually considered to have malignant disease and aspiration biopsy was positive in 28 (93%) of these patients, including 25 of 26 with liver metastases (96%). There were two false-positive results and one minor complication. In 24 patients, conventional wide-bore needle biopsy was also performed. In this group, 16 patients had a final diagnosis of hepatic malignancy. Aspiration biopsies were positive in 14 of these (87%) and conventional needle biopsies were positive in four (25%). Guided percutaneous fine-needle aspiration biopsy is recommended for pathologic diagnosis of hepatic malignancy because of its simplicity, high yield, and reasonable safety.

Authors:
; ; ; ;
Publication Date:
OSTI Identifier:
5392769
Resource Type:
Journal Article
Journal Name:
Cancer (Philadelphia); (United States)
Additional Journal Information:
Journal Volume: 47:7
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; 59 BASIC BIOLOGICAL SCIENCES; LIVER; BIOPSY; NEOPLASMS; DIAGNOSIS; RADIOISOTOPES; DIAGNOSTIC USES; COMPARATIVE EVALUATIONS; METASTASES; PATHOLOGY; PATIENTS; SCINTISCANNING; BODY; COUNTING TECHNIQUES; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM; DISEASES; GLANDS; ISOTOPES; ORGANS; RADIOISOTOPE SCANNING; USES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics; 551001 - Physiological Systems- Tracer Techniques; 550901 - Pathology- Tracer Techniques

Citation Formats

Ho, C.S., McLoughlin, M.J., Tao, L.C., Blendis, L., and Evans, W.K. Guided percutaneous fine-needle aspiration biopsy of the liver. United States: N. p., 1981. Web. doi:10.1002/1097-0142(19810401)47:7<1781::AID-CNCR2820470710>3.0.CO;2-Q.
Ho, C.S., McLoughlin, M.J., Tao, L.C., Blendis, L., & Evans, W.K. Guided percutaneous fine-needle aspiration biopsy of the liver. United States. doi:10.1002/1097-0142(19810401)47:7<1781::AID-CNCR2820470710>3.0.CO;2-Q.
Ho, C.S., McLoughlin, M.J., Tao, L.C., Blendis, L., and Evans, W.K. Wed . "Guided percutaneous fine-needle aspiration biopsy of the liver". United States. doi:10.1002/1097-0142(19810401)47:7<1781::AID-CNCR2820470710>3.0.CO;2-Q.
@article{osti_5392769,
title = {Guided percutaneous fine-needle aspiration biopsy of the liver},
author = {Ho, C.S. and McLoughlin, M.J. and Tao, L.C. and Blendis, L. and Evans, W.K.},
abstractNote = {Forty patients with suspected malignant disease of the liver underwent percutaneous fine-needle aspiration biopsy with radioisotope scintigraphic and fluoroscopic guidance. The needle was aimed at focal defects identified on the liver scan and several passes were made. When the scan was diffusely abnormal, the liver was widely sampled with multiple passes. Thirty patients were eventually considered to have malignant disease and aspiration biopsy was positive in 28 (93%) of these patients, including 25 of 26 with liver metastases (96%). There were two false-positive results and one minor complication. In 24 patients, conventional wide-bore needle biopsy was also performed. In this group, 16 patients had a final diagnosis of hepatic malignancy. Aspiration biopsies were positive in 14 of these (87%) and conventional needle biopsies were positive in four (25%). Guided percutaneous fine-needle aspiration biopsy is recommended for pathologic diagnosis of hepatic malignancy because of its simplicity, high yield, and reasonable safety.},
doi = {10.1002/1097-0142(19810401)47:7<1781::AID-CNCR2820470710>3.0.CO;2-Q},
journal = {Cancer (Philadelphia); (United States)},
number = ,
volume = 47:7,
place = {United States},
year = {1981},
month = {4}
}