Corneal silver deposits following Crede's prophylaxis an examination with electron dispersive x-ray analysis (EDX-analysis) and scanning electron microscope (SEM)

Journal Article · Mon Jan 01 00:00:00 EST 1990 · Lens and Eye Toxicity Research; (United States)

OSTI ID:5391791

Schirner, G; Schrage, N F; Salla, S; Teping, C; Reim, M; Burchard, W G; Schwab, B ^[1]

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1. Augenklinik, RWTH Aachen (Germany)

In a case of silver nitrate injury after Crede's prophylaxis, the cornea of a newborn presented yellow-brown, lime-like plaques on the nasal part of the right eye. A paracentral ulcerating stromal opacification undermined these appositions, when the patient was admitted to the eye-clinic at Aachen. In the material obtained by a lamellar keratectomy scanning electron microscopical examination was able to prove the existence of granules, previously described in light-microscopy. These granules measured 100 to 300 nm in diameter. An earlier chemical analysis of necrotic material showed no silver specific reaction. By means of EDX-analysis these granules could be identified as silver-containing. Injuries by silver nitrate solutions used for Crede's prophylaxis are seldom but still reported. The mechanism of injury in this case of a child, born by sectio remains unknown. Neither the use of an unusual silver nitrate solution, that was taken from a disposable ampoule (Mova-Nitrat R) was reported, nor any corneal injury during sectio mentioned. Nevertheless the method of EDX-analysis and SEM proved the diagnosis of corneal silver deposits, so that the origin of the granullar opacification of the cornea could be determined.

• OSTI ID: 5391791
• Journal Information: Lens and Eye Toxicity Research; (United States), Vol. 7:3-4; ISSN 1042-6922
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
CORNEA
ELECTRON MICROPROBE ANALYSIS
SENSE ORGANS DISEASES
DIAGNOSIS
SILVER
RETENTION
SCANNING ELECTRON MICROSCOPY
BODY
BODY AREAS
CHEMICAL ANALYSIS
DISEASES
ELECTRON MICROSCOPY
ELEMENTS
EYES
FACE
HEAD
METALS
MICROANALYSIS
MICROSCOPY
NONDESTRUCTIVE ANALYSIS
ORGANS
SENSE ORGANS
TRANSITION ELEMENTS
550602* - Medicine- External Radiation in Diagnostics- (1980-)