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Title: Malignant uveal melanoma and similar lesions studied by computed tomography

Abstract

Forty-four patients with intraocular disease were studied by computed tomography (CT); in 19 cases malignant uveal melanoma was considered the likely diagnosis. CT proved to be accurate in determining the location and size of uveal melanomas, demonstrating scleral invasion, and differentiating melanoma from choroidal detachment or angioma, toxocariasis, and senile macular degeneration. On CT, uveal melanomas appeared as hyperdense lesions with slight to moderate contrast enhancement. Tumors thinner than 2 mm could not be seen. Using dynamic CT, the authors noted moderate peak amplitude, normal or delayed tissue transit time, and persistently elevated washout phase (downslope), indicating increased permeability as the result of an impaired tumor blood barrier. Histological types of uveal melanoma could not be differentiated on the basis of circulatory patterns. Dynamic CT may be useful in distinguishing uveal melanoma from choroidal hemangioma or hematoma.

Authors:
; ;
Publication Date:
Research Org.:
Univ. of Illinois, Chicago
OSTI Identifier:
5378476
Alternate Identifier(s):
OSTI ID: 5378476
Report Number(s):
CONF-851152-
Journal ID: CODEN: RADLA
Resource Type:
Conference
Journal Name:
Radiology; (United States)
Additional Journal Information:
Journal Volume: 156:2; Conference: 71. scientific assembly and annual meeting, Chicago, IL, USA, 17 Nov 1985
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; MELANOMAS; DIAGNOSIS; UVEA; COMPUTERIZED TOMOGRAPHY; DYNAMIC FUNCTION STUDIES; PATHOLOGY; PATIENTS; BODY; BODY AREAS; DIAGNOSTIC TECHNIQUES; DISEASES; EYES; FACE; HEAD; NEOPLASMS; ORGANS; SENSE ORGANS; TOMOGRAPHY 550602* -- Medicine-- External Radiation in Diagnostics-- (1980-)

Citation Formats

Mafee, M.F., Peyman, G.A., and McKusick, M.A. Malignant uveal melanoma and similar lesions studied by computed tomography. United States: N. p., 1985. Web.
Mafee, M.F., Peyman, G.A., & McKusick, M.A. Malignant uveal melanoma and similar lesions studied by computed tomography. United States.
Mafee, M.F., Peyman, G.A., and McKusick, M.A. Thu . "Malignant uveal melanoma and similar lesions studied by computed tomography". United States.
@article{osti_5378476,
title = {Malignant uveal melanoma and similar lesions studied by computed tomography},
author = {Mafee, M.F. and Peyman, G.A. and McKusick, M.A.},
abstractNote = {Forty-four patients with intraocular disease were studied by computed tomography (CT); in 19 cases malignant uveal melanoma was considered the likely diagnosis. CT proved to be accurate in determining the location and size of uveal melanomas, demonstrating scleral invasion, and differentiating melanoma from choroidal detachment or angioma, toxocariasis, and senile macular degeneration. On CT, uveal melanomas appeared as hyperdense lesions with slight to moderate contrast enhancement. Tumors thinner than 2 mm could not be seen. Using dynamic CT, the authors noted moderate peak amplitude, normal or delayed tissue transit time, and persistently elevated washout phase (downslope), indicating increased permeability as the result of an impaired tumor blood barrier. Histological types of uveal melanoma could not be differentiated on the basis of circulatory patterns. Dynamic CT may be useful in distinguishing uveal melanoma from choroidal hemangioma or hematoma.},
doi = {},
journal = {Radiology; (United States)},
number = ,
volume = 156:2,
place = {United States},
year = {1985},
month = {8}
}

Conference:
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