Mutagenicity of coal fly ash: a new bioassay for mutagenic potential in a particle feeding ciliate

Journal Article · Thu Jan 01 00:00:00 EST 1981 · Environ. Mutagen.; (United States)

DOI:https://doi.org/10.1002/em.2860030307· OSTI ID:5336289

Smith-Sonneborn, J; Fisher, G L; Palizzi, R A; Herr, C

The use of the established mutagenesis assay in Paramecium as a prescreen for hazardous environmental particles is described. Since these protozoans ingest particles of the size respired by animals and man, the biological effects of the respirable fraction of fly ash particles were monitored in particle-feeding eukaryotic cells. Fly ash from coal combustion was utilized for these studies and was found to be mutagenic. The effects of physical and chemical treatment of the particle mutagenicity provided evidence for both heat-stable, heat-labile and acid extractable mutagenic agents.

• OSTI ID: 5336289
• Journal Information: Environ. Mutagen.; (United States), Vol. 3:3
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
59 BASIC BIOLOGICAL SCIENCES
01 COAL, LIGNITE, AND PEAT
FLY ASH
TOXICITY
PARAMECIUM
BIOLOGICAL EFFECTS
COAL
COMBUSTION
MUTAGEN SCREENING
MUTAGENESIS
PARTICULATES
SENSITIVITY
AEROSOL WASTES
ANIMALS
ASHES
CARBONACEOUS MATERIALS
CHEMICAL REACTIONS
CILIATA
ENERGY SOURCES
FOSSIL FUELS
FUELS
INVERTEBRATES
MATERIALS
MICROORGANISMS
OXIDATION
PARTICLES
PROTOZOA
RESIDUES
SCREENING
THERMOCHEMICAL PROCESSES
WASTES
560302* - Chemicals Metabolism & Toxicology- Microorganisms- (-1987)
550700 - Microbiology
016000 - Coal
Lignite
& Peat- Health & Safety